Anti-PC6 抗体 - Aminoterminal end (ab39873)

製品の概要

  • 製品名
    Anti-PC6 antibody - Aminoterminal end
    PC6 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PC6 - Aminoterminal end
  • 特異性
    ab39873 recognizes the Amino end of the mature enzyme subtilisin like serine protease PC6.
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Rat, Human
  • 免疫原

    Synthetic peptide corresponding to the amino end of mature Human PC6.

    (Peptide available as ab41413.)

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab39873 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
WB
  • 追加情報
    IHC-P: 1/500 (PMID 19339735).
    WB: 1/1000 - 1/5000. Predicted molecular weight: 101 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Likely to represent a widespread endoprotease activity within the constitutive and regulated secretory pathway. Capable of cleavage at the RX(K/R)R consensus motif.
    • 組織特異性
      Expressed in T-lymphocytes.
    • 配列類似性
      Belongs to the peptidase S8 family.
      Contains 1 homo B/P domain.
      Contains 1 PLAC domain.
    • ドメイン
      The propeptide domain acts as an intramolecular chaperone assisting the folding of the zymogen within the endoplasmic reticulum.
    • 細胞内局在
      Secreted.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ11149 antibody
      • FLJ16215 antibody
      • hPC6 antibody
      • PC5 antibody
      • PC6 antibody
      • PC6A antibody
      • Pcsk5 antibody
      • PCSK5_HUMAN antibody
      • Prohormone convertase 5 antibody
      • Proprotein convertase 5 antibody
      • Proprotein convertase 6 antibody
      • Proprotein convertase PC5 antibody
      • Proprotein convertase subtilisin/kexin type 5 antibody
      • Protease PC6 antibody
      • SPC6 antibody
      • Subtilisin/kexin-like protease PC5 antibody
      see all

    プロトコール

    Anti-PC6 antibody - Aminoterminal end (ab39873) 使用論文

    This product has been referenced in:
    • Sathyamurthy M  et al. Characterization and expression of proprotein convertases in CHO cells: Efficient proteolytic maturation of human bone morphogenetic protein-7. Biotechnol Bioeng N/A:N/A (2014). WB . Read more (PubMed: 25219685) »
    • Zhou Z  et al. The proprotein convertase furin is required for trophoblast syncytialization. Cell Death Dis 4:e593 (2013). WB ; Mouse, Human . Read more (PubMed: 23598405) »

    See all 3 Publications for this product

    Product Wall

    Application
    Immunocytochemistry
    Sample
    Human Cultured Cells (pancreatic cancer cells)
    Permeabilization
    Yes - 0.1% Tween20
    Specification
    pancreatic cancer cells
    Blocking step
    BSA as blocking agent for 1 hour(s) and 30 minute(s) · Concentration: 1%
    Fixative
    Paraformaldehyde
    Username

    Abcam user community

    Verified customer

    投稿 Nov 15 2016

    Abcam guarantees this product to work in the species/application used in this Abreview.
    Application
    Western blot
    Sample
    Rat Cell lysate - whole cell (rat ovary primary cultured cell)
    Loading amount
    50 µg
    Specification
    rat ovary primary cultured cell
    Treatment
    LH hormone
    Gel Running Conditions
    Reduced Denaturing (8%)
    Blocking step
    Milk as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: 25°C
    Username

    Abcam user community

    Verified customer

    投稿 May 31 2012

    We do not routinely offer free or trial sized samples for testing purposes. Our policy at Abcam is that if an antibody does not work as specified on the datasheet, we will offer a replacement or reimbursement. If the antibody is being used in an untes...

    Read More

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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