製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to PBXIP1
  • アプリケーション
    適用あり: IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Chimpanzee, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide corresponding to a region between amino acids 175 and 225 of human PBXIP1 (NP_079033.3).

  • ポジティブ・コントロール
    • Breast carcinoma, ovarian carcinoma,anaplastic tyroid carcinoma,pancreatic islet cell tumor,stomach adenocarcinoma,testicular seminoma,stomach adenocarcinoma,prostrate carcinoma,linitis plastica stomach cancer,metastatic lymph node,teratoma

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab84752 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報
    IHC-P: 1/100 - 1/500. Epitope exposure is recommended.
    Epitope exposure with citrate buffer will enhance staining.

    Likely to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性
      PBXIP1 is a regulator of pre-B-cell leukemia transcription factors (BPXs) function. It inhibits the binding of PBX1-HOX complex to DNA and blocks the transcriptional activity of E2A-PBX1. PBXIP1 also tethers estrogen receptor-alpha (ESR1) to microtubules and allows them to influence estrogen receptors-alpha signaling.
    • 細胞内局在
      Cytoplasm, cytoskeleton. Nucleus. Note=Shuttles between the nucleus and the cytosol. Mainly localized in the cytoplasm, associated with microtubules. Detected in small amounts in the nucleus.
    • 参照データベース
    • 別名
      • 4732463H20Rik antibody
      • Hematopoietic PBX interacting protein antibody
      • HPIP antibody
      • MGC38361 antibody
      • Pre B cell leukemia homeobox interacting protein 1 antibody
      • RP11-307C12.2 antibody
      see all

    画像

    • Detection of mouse HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of mouse teratoma , using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry on formalin fixed, paraffin embedded sections of human ovarian carcinoma, using ab84752 at a 1/100 dilution.
      Detection: DAB staining.
    • Detection of human HPIP by immunohistochemistry immunofluorescence of human ovarian carcinoma, using ab84752 at 1/100 dilution.
      Detection: red fluorescent Goat anti-Rabbit IgG diluted 1/100.

    プロトコール

    参考文献

    ab84752 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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