Anti-PBX1 抗体 [146C1a] (ab66496)

製品の概要

  • 製品名Anti-PBX1 antibody [146C1a]
    PBX1 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [146C1a] to PBX1
  • アプリケーション適用あり: WB, Dot blotmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant fragment from the internal region of human PBX1

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab66496 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Predicted molecular weight: 47 kDa.
Dot blot Use at an assay dependent dilution.

ターゲット情報

  • 機能Binds the sequence 5'-ATCAATCAA-3'. Acts as a transcriptional activator of PF4 in complex with MEIS1. Converted into a potent transcriptional activator by the (1;19) translocation. May have a role in steroidogenesis and, subsequently, sexual development and differentiation.
  • 組織特異性Expressed in all tissues except in cells of the B and T lineage.
  • 関連疾患Note=A chromosomal aberration involving PBX1 is a cause of pre-B-cell acute lymphoblastic leukemia (B-ALL). Translocation t(1;19)(q23;p13.3) with TCF3. E2A-PBX1 transforms cells by constitutively activating transcription of genes regulated by PBX1 or by other members of the PBX protein family.
  • 配列類似性Belongs to the TALE/PBX homeobox family.
    Contains 1 homeobox DNA-binding domain.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • DKFZp686B09108 antibody
    • Homeo box protein PBX1 antibody
    • Homeo box protein PRL antibody
    • Homeobox protein PBX 1 antibody
    • Homeobox protein PBX1 antibody
    • Homeobox protein PRL antibody
    • MGC126627 antibody
    • PBX 1 antibody
    • Pbx1 antibody
    • PBX1_HUMAN antibody
    • Pre B cell leukemia homeobox 1 antibody
    • Pre B cell leukemia transcription factor 1 antibody
    • Pre-B-cell leukemia transcription factor 1 antibody
    • PRL antibody
    see all

Anti-PBX1 antibody [146C1a] 画像

Anti-PBX1 antibody [146C1a] (ab66496) 使用論文

ab66496 has not yet been referenced specifically in any publications.

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Thank you for your email last week and for your patience. I have heard back from the testing laboratory, and unfortunately the antibody has not been specifically tested against the isoform B. However, we do have a PBX1 antibody that I would expect to r...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"