製品の概要

  • 製品名Anti-PAX8 antibody
    PAX8 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal to PAX8
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Recombinant full length Human protein (AAH01060) with a proprietary tag.

  • ポジティブ・コントロール
    • Liver tissue lysate; LNCap or Hs 181.Tes cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab89508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 5 µg/ml. Predicted molecular weight: 48 kDa.
ELISA Use at an assay dependent dilution.

ターゲット情報

  • 機能Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.
  • 組織特異性Expressed in the excretory system, thyroid gland and Wilms tumors.
  • 関連疾患Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2) [MIM:218700]. CHNG2 is a disease characterized by thyroid dysgenesis, the most frequent cause of congenital hypothyroidism, accounting for 85% of case. The thyroid gland can be completely absent (athyreosis), ectopically located and/or severely hypoplastic. Ectopic thyroid gland is the most frequent malformation, with thyroid tissue being found most often at the base of the tongue.
  • 配列類似性Contains 1 paired domain.
  • 発生段階In developing excretory system, during thyroid differentiation and in adult thyroid.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • OTTHUMP00000158659 antibody
    • OTTHUMP00000158660 antibody
    • OTTHUMP00000203723 antibody
    • OTTHUMP00000203724 antibody
    • Paired box 8 antibody
    • Paired box gene 8 antibody
    • paired box homeotic gene 8 antibody
    • Paired box protein Pax 8 antibody
    • Paired box protein Pax-8 antibody
    • Paired domain gene 8 antibody
    • PAX 8 antibody
    • PAX8 antibody
    • PAX8_HUMAN antibody
    see all

Anti-PAX8 antibody 画像

  • Anti-PAX8 antibody (ab89508) at 5 µg/ml + Human liver lysate at 50 µg

    Predicted band size : 48 kDa
  • Anti-PAX8 antibody (ab89508) at 5 µg/ml + LNCaP cell lysate at 50 µg

    Predicted band size : 48 kDa
  • Anti-PAX8 antibody (ab89508) at 5 µg/ml + Hs 181.Tes cell lysate at 50 µg

    Predicted band size : 48 kDa
  • Anti-PAX8 antibody (ab89508) at 5 µg/ml + immunogen (full length recombinant protein with a tag of 26kDa) at 0.2 µg

    Predicted band size : 48 kDa
    Observed band size : 75 kDa (why is the actual band size different from the predicted?)

Anti-PAX8 antibody (ab89508) 使用論文

ab89508 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab89508.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"