製品の概要

  • 製品名Anti-PAX8 antibody
    PAX8 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PAX8
  • アプリケーション適用あり: ELISA, WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    3 synthetic peptides (human) conjugated to KLH

  • ポジティブ・コントロール
    • Induced culture of E.coli (one shot Top10 competent cells).

法規制情報

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab82845 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA
WB
  • 追加情報ELISA: Use at an assay dependent dilution.
    Antibody specificity was verified by direct ELISA against the 3 immunogen peptides. A minimum titer of 1/50000 is determined for one of the three peptides.
    WB: 1/1000. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Transcription factor for the thyroid-specific expression of the genes exclusively expressed in the thyroid cell type, maintaining the functional differentiation of such cells.
    • 組織特異性Expressed in the excretory system, thyroid gland and Wilms tumors.
    • 関連疾患Defects in PAX8 are the cause of congenital hypothyroidism non-goitrous type 2 (CHNG2) [MIM:218700]. CHNG2 is a disease characterized by thyroid dysgenesis, the most frequent cause of congenital hypothyroidism, accounting for 85% of case. The thyroid gland can be completely absent (athyreosis), ectopically located and/or severely hypoplastic. Ectopic thyroid gland is the most frequent malformation, with thyroid tissue being found most often at the base of the tongue.
    • 配列類似性Contains 1 paired domain.
    • 発生段階In developing excretory system, during thyroid differentiation and in adult thyroid.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • OTTHUMP00000158659 antibody
      • OTTHUMP00000158660 antibody
      • OTTHUMP00000203723 antibody
      • OTTHUMP00000203724 antibody
      • Paired box 8 antibody
      • Paired box gene 8 antibody
      • paired box homeotic gene 8 antibody
      • Paired box protein Pax 8 antibody
      • Paired box protein Pax-8 antibody
      • Paired domain gene 8 antibody
      • PAX 8 antibody
      • PAX8 antibody
      • PAX8_HUMAN antibody
      see all

    Anti-PAX8 antibody 画像

    • All lanes : Anti-PAX8 antibody (ab82845) at 1/1000 dilution

      Lane 1 : uninduced culture of E.coli (one shot Top10 competent cells)
      Lane 2 : induced culture of E.coli (one shot Top10 competent cells)

      Secondary
      anti-Rabbit IgG HRP at 1/1000 dilution

      Predicted band size : 62 kDa
      Observed band size : 62 kDa
      Additional bands at : 40 kDa,50 kDa. We are unsure as to the identity of these extra bands.

    Anti-PAX8 antibody (ab82845) 使用論文

    ab82845 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab82845.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"