製品の概要

  • 製品名
  • 製品の詳細
    Mouse monoclonal to PAX7
  • アプリケーション
    適用あり: WB, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Recombinant fragment, corresponding to amino acids 411-521 of Human PAX7

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab55494 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
IHC-P
  • 追加情報
    WB: Use at a concentration of 1-5 µg/ml.
    IHC-P: Use at a concentration of 5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能
      Probable transcription factor. May have a role in myogenesis.
    • 関連疾患
      Defects in PAX7 are a cause of rhabdomyosarcoma type 2 (RMS2) [MIM:268220]. It is a form of rhabdomyosarcoma, a highly malignant tumor of striated muscle derived from primitive mesenchimal cells and exhibiting differentiation along rhabdomyoblastic lines. Rhabdomyosarcoma is one of the most frequently occurring soft tissue sarcomas and the most common in children. It occurs in four forms: alveolar, pleomorphic, embryonal and botryoidal rhabdomyosarcomas. Note=A chromosomal aberration involving PAX7 is found in rhabdomyosarcoma. Translocation t(1;13)(p36;q14) with FOXO1. The resulting protein is a transcriptional activator.
    • 配列類似性
      Belongs to the paired homeobox family.
      Contains 1 homeobox DNA-binding domain.
      Contains 1 paired domain.
    • 細胞内局在
      Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • FLJ37460 antibody
      • HUP1 antibody
      • OTTHUMP00000002534 antibody
      • Paired box 7 antibody
      • Paired box gene 7 antibody
      • Paired box homeotic gene 7 antibody
      • Paired box protein Pax-7 antibody
      • Paired domain gene 7 antibody
      • Paired domain gene HuP1 antibody
      • Pax7 antibody
      • PAX7 transcriptional factor antibody
      • PAX7/FKHR fusion gene, included antibody
      • PAX7_HUMAN antibody
      • PAX7B antibody
      • RGD1564360 antibody
      • RMS2 antibody
      see all

    Anti-PAX7 antibody 画像

    • PAX7 antibody (ab55494) used in immunohistochemistry at 5ug/ml on formalin fixed and paraffin embedded human stomach.


    • Predicted band size : 57 kDa

    Anti-PAX7 antibody (ab55494) 使用論文

    This product has been referenced in:
    • Katare R  et al. Clinical-grade human neural stem cells promote reparative neovascularization in mouse models of hindlimb ischemia. Arterioscler Thromb Vasc Biol 34:408-18 (2014). Read more (PubMed: 24202301) »
    • Hamilton DF  et al. Muscle 'regenerative potential' determinesphysical recovery following total knee replacement. Bone Joint Res 2:70-8 (2013). IHC-P ; Human . Read more (PubMed: 23673375) »

    See all 2 Publications for this product

    Product Wall

    Application
    Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
    Antigen retrieval step
    Heat mediated - Buffer/Enzyme Used: CC1
    Sample
    Human Tissue sections (Tonsil)
    Specification
    Tonsil
    Permeabilization
    No
    Fixative
    Formaldehyde
    Username

    Abcam user community

    Verified customer

    投稿 Jan 28 2015

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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