製品の概要

  • 製品名Anti-PAX5 antibody [1EW]
    PAX5 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [1EW] to PAX5
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length native PAX5 (purified) (Human)

  • ポジティブ・コントロール
    • Human acute lymphoblastic leukemia

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab67005 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P
  • 追加情報IHC-P: 1/20 - 1/40.
    heat induced epitope retrieval for paraffin sections using 10mM citrate buffer (pH6.0) is recommended.

    Note: When utilized in immunohistochemistry, the use of H2O2 to block endogenous peroxidase has been shown to have a detrimental effect on the epitope recognised by ab67005. It is, therefore, CRITICAL that blocking with H2O2 should be carried out after application of the primary antibody with solutions of no greater than 3%. If these recommendations are not followed, staining intensity will be reduced.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能May play an important role in B-cell differentiation as well as neural development and spermatogenesis. Involved in the regulation of the CD19 gene, a B-lymphoid-specific target gene.
    • 関連疾患A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia. Translocation t(9;18)(p13;q11.2) with ZNF521. Translocation t(9;3)(p13;p14.1) with FOXP1. Translocation t(9;12)(p13;p13) with ETV6.
      Leukemia, acute lymphoblastic, 3
    • 配列類似性Contains 1 paired domain.
    • 発生段階Expressed at early B-cell differentiation, in the developing CNS and in adult testis.
    • 翻訳後修飾O-glycosylated.
    • 細胞内局在Nucleus.
    • Information by UniProt
    • 参照データベース
    • 別名
      • B cell lineage specific activator antibody
      • B cell lineage specific activator protein antibody
      • B cell specific activator protein antibody
      • B cell specific transcription factor antibody
      • B-cell-specific transcription factor antibody
      • BSAP antibody
      • EBB-1 antibody
      • KLP antibody
      • Paired box 5 antibody
      • Paired box gene 5 (B cell lineage specific activator protein) antibody
      • Paired box gene 5 (B cell lineage specific activator) antibody
      • Paired box gene 5 antibody
      • Paired box homeotic gene 5 antibody
      • Paired box protein Pax 5 antibody
      • Paired box protein Pax-5 antibody
      • Paired domain gene 5 antibody
      • PAX 5 antibody
      • PAX5 antibody
      • PAX5_HUMAN antibody
      • Transcription factor PAX 5 antibody
      see all

    Anti-PAX5 antibody [1EW] 画像

    • Human acute lymphoblastic leukemia: immunohistochemical staining for Pax5 with 1/20 ab67005. Note nuclear staining of B cells. Paraffin section.

    Anti-PAX5 antibody [1EW] (ab67005) 使用論文

    ab67005 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab67005.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"