製品の概要

  • 製品名Anti-PARP2 antibody
    PARP2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PARP2
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Cow
  • 免疫原

    Synthetic peptide conjugated to KLH derived from within residues 550 to the C-terminus of Human PARP2.

  • ポジティブ・コントロール
    • This antibody gave a positive signal in the following tissue lysates: Human brain; Human pancreas; Human testis.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab93841 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 66 kDa (predicted molecular weight: 66 kDa).

ターゲット情報

  • 機能Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
  • 組織特異性Widely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
  • 配列類似性Contains 1 PARP alpha-helical domain.
    Contains 1 PARP catalytic domain.
  • 翻訳後修飾Poly-ADP-ribosylated by PARP1.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosyltransferase like 2 antibody
    • ADP-ribosyltransferase diphtheria toxin-like 2 antibody
    • ADPRT 2 antibody
    • ADPRT-2 antibody
    • ADPRT2 antibody
    • ADPRTL 2 antibody
    • ADPRTL 3 antibody
    • ADPRTL2 antibody
    • ADPRTL3 antibody
    • ARTD2 antibody
    • hPARP 2 antibody
    • hPARP-2 antibody
    • hPARP2 antibody
    • NAD(+) ADP ribosyltransferase 2 antibody
    • NAD(+) ADP-ribosyltransferase 2 antibody
    • pADPRT 2 antibody
    • pADPRT-2 antibody
    • pADPRT2 antibody
    • PARP 2 antibody
    • PARP-2 antibody
    • PARP2 antibody
    • PARP2_HUMAN antibody
    • Poly (ADP ribose) polymerase family member 2 antibody
    • Poly (ADP ribosyl) transferase like 2 antibody
    • poly (ADP-ribose) polymerase 2 antibody
    • Poly [ADP ribose] synthetase 2 antibody
    • Poly [ADP-ribose] polymerase 2 antibody
    • Poly(ADP ribose) synthetase antibody
    • Poly[ADP-ribose] synthase 2 antibody
    see all

Anti-PARP2 antibody 画像

  • All lanes : Anti-PARP2 antibody (ab93841) at 1 µg/ml

    Lane 1 : Human brain tissue lysate - total protein (ab29466)
    Lane 2 : Human pancreas tissue lysate - total protein (ab29816)
    Lane 3 : Human testis tissue lysate - total protein (ab30257)

    Lysates/proteins at 10 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 66 kDa
    Observed band size : 66 kDa
    Additional bands at : 57 kDa. We are unsure as to the identity of these extra bands.

    Exposure time : 8 minutes

Anti-PARP2 antibody (ab93841) 使用論文

ab93841 has not yet been referenced specifically in any publications.

Product Wall

Thank you very much for your interest in ab93841.

Unfortunately, the immunogen has only about 66% of identity with the arabidopsis sequence. The possibility of crossreaction is therefore low. Please see here for the alignment yourself:
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"