製品の概要

  • 製品名Anti-PARP2 antibody
    PARP2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to PARP2
  • アプリケーション適用あり: WB, IHC-P, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    LDLFEVEKDGEKE

    with a Cysteine residue linker, corresponding to internal sequence amino acids 402-414 of Human PARP2 (NP_005475.2).

  • ポジティブ・コントロール
    • Human Adrenal andSkin tissues; Human Spleen lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab115620 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Predicted molecular weight: 66 kDa.
IHC-P Use a concentration of 2.5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
ELISA 1/8000.

ターゲット情報

  • 機能Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
  • 組織特異性Widely expressed, mainly in actively dividing tissues. The highest levels are in the brain, heart, pancreas, skeletal muscle and testis; also detected in kidney, liver, lung, placenta, ovary and spleen; levels are low in leukocytes, colon, small intestine, prostate and thymus.
  • 配列類似性Contains 1 PARP alpha-helical domain.
    Contains 1 PARP catalytic domain.
  • 翻訳後修飾Poly-ADP-ribosylated by PARP1.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP ribosyltransferase like 2 antibody
    • ADP-ribosyltransferase diphtheria toxin-like 2 antibody
    • ADPRT 2 antibody
    • ADPRT-2 antibody
    • ADPRT2 antibody
    • ADPRTL 2 antibody
    • ADPRTL 3 antibody
    • ADPRTL2 antibody
    • ADPRTL3 antibody
    • ARTD2 antibody
    • hPARP 2 antibody
    • hPARP-2 antibody
    • hPARP2 antibody
    • NAD(+) ADP ribosyltransferase 2 antibody
    • NAD(+) ADP-ribosyltransferase 2 antibody
    • pADPRT 2 antibody
    • pADPRT-2 antibody
    • pADPRT2 antibody
    • PARP 2 antibody
    • PARP-2 antibody
    • PARP2 antibody
    • PARP2_HUMAN antibody
    • Poly (ADP ribose) polymerase family member 2 antibody
    • Poly (ADP ribosyl) transferase like 2 antibody
    • poly (ADP-ribose) polymerase 2 antibody
    • Poly [ADP ribose] synthetase 2 antibody
    • Poly [ADP-ribose] polymerase 2 antibody
    • Poly(ADP ribose) synthetase antibody
    • Poly[ADP-ribose] synthase 2 antibody
    see all

Anti-PARP2 antibody 画像

  • ab115620, at 2.5µg/ml, staining PARP2 in Formalin-fixed, Paraffin-embedded Human Adrenal tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • ab115620, at 2.5µg/ml, staining PARP2 in Formalin-fixed, Paraffin-embedded Human Skin tissue by Immunohistochemistry followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen.
  • Anti-PARP2 antibody (ab115620) at 1 µg/ml + Human Spleen Lysate at 35 µg
    Developed using the ECL technique

    Predicted band size : 66 kDa

Anti-PARP2 antibody (ab115620) 使用論文

ab115620 has not yet been referenced specifically in any publications.

Product Wall

Application Immunocytochemistry/ Immunofluorescence
Sample Human Cell (HeLa)
Permeabilization Yes - 0.5% TritonX100 in PBS
Specification HeLa
Fixative Paraformaldehyde
Username

Dr. Kirk McManus

Verified customer

投稿 Aug 07 2015

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"