Synthetic peptide corresponding to a region between residues 300 and 350 of human PARP10 (NP_116178.1).
Human controls: Anaplastic Thyroid Carcinoma, Breast Carcinoma, Laryngeal Squamous Cell Carcinoma, Non-Small Cell Lung Cancer, Ovarian Carcinoma, Small Cell Lung Cancer
Mouse control: Squamous Cell Carcinoma
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium Azide
Constituents: 0.1% BSA, Tris buffered saline
Concentration information loading...
Immunogen affinity purified
ab84917 was affinity purified using an epitope specific to PARP10 immobilized on solid support. Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
IHC-P: 1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining.
Likely to work with frozen sections.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Poly (ADP ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP ribose to histones. PARPs can also function as transcriptional cofactors