Anti-Parathyroid Hormone 抗体 [D1.5] (ab14501)

製品の概要

  • 製品名Anti-Parathyroid Hormone antibody [D1.5]
    Parathyroid Hormone 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [D1.5] to Parathyroid Hormone
  • 特異性Ab14501 reacts with parathyroid hormone peptides (aa 53-68; 53-84; 7-84; 1-84); affinity: > 2 x 1010 l/mol. There are no cross reactivities with synthetic parathyroid hormone peptides (aa 1-10; 1-34; 1-38).
  • アプリケーション適用あり: ELISA, IHC-P, IHC-Frmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Cow, Dog, Cynomolgus Monkey
  • 免疫原

    bTG conjugated synthetic peptide:

    KKEDNVLVESHEKSLGEADKADVNVLTKAKSQ

    , corresponding to amino acids 53-84 of Human Parathyroid Hormone.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: None
    Constituents: 0.1M PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • ポリ/モノモノクローナル
  • クローン名D1.5
  • アイソタイプIgG1
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab14501 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use at an assay dependent concentration. Use at a concentration of 500 ng/ml.
ILMA: Use at a concentration of 500 ng/ml.
IHC-P Use a concentration of 2 µg/ml.
IHC-Fr Use a concentration of 2 µg/ml.

ターゲット情報

  • 機能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 関連疾患Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 配列類似性Belongs to the parathyroid hormone family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody [D1.5] (ab14501) 使用論文

ab14501 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"