Anti-Parathyroid Hormone 抗体 [A1/70] (ab14493)

製品の概要

  • 製品名Anti-Parathyroid Hormone antibody [A1/70]
    Parathyroid Hormone 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [A1/70] to Parathyroid Hormone
  • 特異性ab14493 recognises parathyroid hormone peptides (aa 15-25; 1-34; 1-38; 1-84; 7-84). There are no cross reactivities obtained with synthetic parathyroid hormone peptides (aa 1-3; 1-10; 4-16; 28-48; 39-84; 44-68; 53-84) and PTHrP (aa 1-86).
  • アプリケーション適用あり: ELISA, RIA, IHC-Fr, IHC-P, Sandwich ELISAmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Cow, Cat, Dog, Pig, Cynomolgus Monkey
  • 免疫原

    Poly lysin conjugated synthetic peptide:

    SVSEIQLMHNLGKHLNSMERVEWLRKKLQDVHNFVALG

    , corresponding to amino acids 1-38 of Human Parathyroid Hormone.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 0.15M Sodium Chloride, 0.01M Sodium Phosphate. pH 7.2
  • Concentration information loading...
  • 精製度Protein A purified
  • 特記事項(精製)Cell supernatant, Prot. A purified.
  • ポリ/モノモノクローナル
  • クローン名A1/70
  • アイソタイプIgA
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab14493 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
ELISA Use a concentration of 1 µg/ml.
RIA Use at an assay dependent concentration. Use at a concentration of 2 ng/ml
IHC-Fr Use a concentration of 2 µg/ml.
IHC-P Use a concentration of 2 µg/ml.
Sandwich ELISA Use a concentration of 0.2 µg/ml. Can be paired for Sandwich ELISA with Rabbit polyclonal to Parathyroid Hormone (ab53040). For sandwich ELISA, use this antibody as Capture at 0.2µg/ml with ab53040 as Detection.

ターゲット情報

  • 機能PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 関連疾患Defects in PTH are a cause of familial isolated hypoparathyroidism (FIH) [MIM:146200]; also called autosomal dominant hypoparathyroidism or autosomal dominant hypocalcemia. FIH is characterized by hypocalcemia and hyperphosphatemia due to inadequate secretion of parathyroid hormone. Symptoms are seizures, tetany and cramps. FIH exist both as autosomal dominant and recessive forms of hypoparathyroidism.
  • 配列類似性Belongs to the parathyroid hormone family.
  • 細胞内局在Secreted.
  • Information by UniProt
  • 参照データベース
  • 別名
    • hPTH antibody
    • Parathormone antibody
    • Parathyrin antibody
    • Parathyroid hormone 1 antibody
    • Parathyroid hormone antibody
    • PTH antibody
    • PTH1 antibody
    • PTH1 receptor antibody
    • PTH1R antibody
    • PTHR antibody
    • PTHR1 antibody
    • PTHY_HUMAN antibody
    see all

Anti-Parathyroid Hormone antibody [A1/70] 画像

プロトコール

Anti-Parathyroid Hormone antibody [A1/70] (ab14493) 使用論文

ab14493 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"