製品の概要
- 製品名Anti-PAR6 antibody
PAR6 一次抗体 製品一覧 - 製品の詳細Rabbit polyclonal to PAR6
- アプリケーション適用あり: WB, ICC/IFmore details
- 種交差性交差種: Human
- 免疫原
A peptide from the n-terminal and a peptide from the c-terminal region of PAR6 conjugated to KLH and co-immunized into rabbits
製品の特性
- 製品の状態Liquid
- 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
- バッファーPreservative: 0.05% Sodium azide
Constituent: 99.95% Whole serum - 精製度Whole antiserum
- ポリ/モノポリクローナル
- アイソタイプIgG
- 研究分野
関連製品
- Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab111823 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | 1/1000. Predicted molecular weight: 37 kDa. | |
| ICC/IF | 1/100. |
ターゲット情報
- 機能Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
- 組織特異性Expressed in pancreas, skeletal muscle, brain and heart. Weakly expressed in kidney and placenta.
- 配列類似性Belongs to the PAR6 family.
Contains 1 OPR domain.
Contains 1 PDZ (DHR) domain.
Contains 1 pseudo-CRIB domain. - ドメインThe pseudo-CRIB domain together with the PDZ domain is required for the interaction with Rho small GTPases.
The OPR domain mediates interactions with MAP2K5.
The PDZ domain mediates the interaction with CRB3. - 細胞内局在Cytoplasm. Cell membrane. Cell projection > ruffle. Cell junction > tight junction. Colocalizes with GTP-bound CDC42 or RAC1 at membrane ruffles and with PARD3 and PRKCI at epithelial tight junctions.
- Information by UniProt
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参照データベース
- Entrez Gene: 50855 Human
- Omim: 607484 Human
- SwissProt: Q9NPB6 Human
- Unigene: 112933 Human
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別名
- 0710008C04Rik antibody
- 2610010A15Rik antibody
- Par 6 partitioning defective 6 C elegans homolog alpha antibody
see all
Anti-PAR6 antibody (ab111823) 使用論文
ab111823 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"