Anti-PANK1 抗体 (ab96173)
Key features and details
- Rabbit polyclonal to PANK1
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PANK1 antibody
PANK1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PANK1 -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Zebrafish -
免疫原
Recombinant fragment, corresponding to a region within amino acids 207-483 of Human PANK1.
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ポジティブ・コントロール
- 293T, A431, H1299, HeLa S3, HepG2, Molt-4, Raji cells, NCIN87 xenograft
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles. -
バッファー
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 10% Glycerol (glycerin, glycerine) -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab96173の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
1/500 - 1/3000. Predicted molecular weight: 64 kDa.
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IHC-P |
1/100 - 1/500.
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特記事項 |
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WB
1/500 - 1/3000. Predicted molecular weight: 64 kDa. |
IHC-P
1/100 - 1/500. |
ターゲット情報
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機能
Plays a role in the physiological regulation of the intracellular CoA concentration. -
組織特異性
Isoform 1 is expressed at high levels in brain, heart, kidney, liver, skeletal muscle and testis. Isoform 2 is detected at much lower levels in kidney, liver, brain and testis and is not detected in heart or skeletal muscle. -
パスウェイ
Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5. -
配列類似性
Belongs to the type II pantothenate kinase family. -
ドメイン
The N-terminal extension, present in isoform 1 may be the regulatory domain. -
細胞内局在
Cytoplasm. - Information by UniProt
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参照データベース
- Entrez Gene: 53354 Human
- Entrez Gene: 75735 Mouse
- Entrez Gene: 294088 Rat
- Omim: 606160 Human
- SwissProt: Q8TE04 Human
- SwissProt: Q8K4K6 Mouse
- Unigene: 376351 Human
- Unigene: 24742 Mouse
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別名
- coaA antibody
- hPanK antibody
- hPanK1 antibody
see all
画像
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (2)
ab96173 は 2 報の論文で使用されています。
- Zhang Y et al. Inhibition of miR-15a-5p Promotes the Chemoresistance to Pirarubicin in Hepatocellular Carcinoma via Targeting eIF4E. Comput Math Methods Med 2021:6468405 (2021). PubMed: 34812269
- Machado MV et al. Vitamin B5 and N-Acetylcysteine in Nonalcoholic Steatohepatitis: A Preclinical Study in a Dietary Mouse Model. Dig Dis Sci 61:137-48 (2016). PubMed: 26403427