PANC-1 nuclear extract lysate (ab14882)

製品の概要

  • 製品名PANC-1 nuclear extract lysate
  • 特記事項Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA). To ensure stability, we recommend aliquoting the extracts into single-use fractions and then storing them at -80ºC.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
  • バッファーPreservative: None
    Constituents: 20% Glycerol, 20mM HEPES, 100mM Potassium Chloride, 1mM Magnesium Chloride, 0.5mM PMSF, 0.5mM DTT. pH 7.9
  • Concentration information loading...
  • 研究分野
  • 背景PANC-1 cells are used as an in vitro model of non-endocrine pancreatic cancer for tumorigenicity studies. The cells possess the type B phenotype for glucose-6-phosphate dehydrogenase G6PD and overexpress heregulin/human epidermal growth-factor receptor 2 (HER2/neu) oncogene (which is present in 60-70% of human pancreatic carcinomas) but are estrogen receptor (ER) negative. Cells are also negative for MUC4 (Sialomucin complex SMC, an intramembrane ligand for ErbB2) and positive for Smad4 (a TGF beta signalling cascade protein inactivated in human gastrointestinal cancers).

PANC-1 nuclear extract lysate (ab14882) 使用論文

ab14882 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"