PANC-1 nuclear extract lysate (ab14882)
製品の概要
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製品名
PANC-1 nuclear extract lysate -
特記事項
Extracts have been quality control tested by Western blot and the Electrophoretic Mobility Shift Assay (EMSA).
製品の特性
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Mycoplasma free
Yes -
製品の状態
Liquid -
保存方法
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles. -
バッファー
pH: 7.90
Constituents: 0.75% Potassium chloride, 0.009% PMSF, 0.01% Magnesium chloride, 0.008% DTT, 0.48% HEPES, 20% Glycerol -
Concentration information loading...
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研究分野
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背景
PANC-1 cells are used as an in vitro model of non-endocrine pancreatic cancer for tumorigenicity studies. The cells possess the type B phenotype for glucose-6-phosphate dehydrogenase G6PD and overexpress heregulin/human epidermal growth-factor receptor 2 (HER2/neu) oncogene (which is present in 60-70% of human pancreatic carcinomas) but are estrogen receptor (ER) negative. Cells are also negative for MUC4 (Sialomucin complex SMC, an intramembrane ligand for ErbB2) and positive for Smad4 (a TGF beta signalling cascade protein inactivated in human gastrointestinal cancers).
プロトコール
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (0)
ab14882 は論文での使用が確認できていません。