Anti-pan Cytokeratin 抗体 [C-11] (Allophycocyanin) (ab106166)

製品の概要

  • 製品名Anti-pan Cytokeratin antibody [C-11] (Allophycocyanin)
    pan Cytokeratin 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [C-11] to pan Cytokeratin (Allophycocyanin)
  • 標識Allophycocyanin. Ex: 645nm, Em: 660nm
  • 特異性ab106166 reacts with Cytokeratin peptides 4, 5, 6, 8, 10, 13, 18.
  • アプリケーション適用あり: Flow Cytmore details
  • 種交差性

    交差が予測される動物種: all Mammals
  • 免疫原

    Keratin-enriched preparation from Human epidermoid carcinoma cell line A431.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab106166 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt Use a concentration of 5 µg/ml. ab37391-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

ターゲット情報

  • 関連性Cytokeratins, a group comprising at least 29 different proteins, are characteristic of epithelial and trichocytic cells. Cytokeratins 1, 4, 5, 6, and 8 are members of the type II neutral to basic subfamily. Monoclonal anti cytokeratins are specific markers of epithelial cell differentiation and have been widely used as tools in tumor identification and classification. Monoclonal Anti Pan Cytokeratin (mixture) is a broadly reactive reagent, which recognizes epitopes present in most human epithelial tissues. It facilitates typing of normal, metaplastic and neoplastic cells. Synergy between the various components results in staining amplification. This enables identification of cells, which would otherwise be stained only marginally. The mixture may aid in the discrimination of carcinomas and nonepithelial tumors such as sarcomas, lymphomas and neural tumors. It is also useful in detecting micrometastases in lymph nodes, bone marrow and other tissues and for determining the origin of poorly differentiated tumors. There are two types of cytokeratins the acidic type I cytokeratins and the basic or neutral type II cytokeratins. Cytokeratins are usually found in pairs comprising a type I cytokeratin and a type II cytokeratin. Usually the type II cytokeratins are 8kD larger than their type I counterparts.
  • 細胞内局在Cytoplasmic

Anti-pan Cytokeratin antibody [C-11] (Allophycocyanin) (ab106166) 使用論文

This product has been referenced in:
  • Turner ML  et al. Epithelial and stromal cells of bovine endometrium have roles in innate immunity and initiate inflammatory responses to bacterial lipopeptides in vitro via Toll-like receptors TLR2, TLR1, and TLR6. Endocrinology 155:1453-65 (2014). Flow Cyt ; Cow . Read more (PubMed: 24437488) »
  • Hamakawa H  et al. Extraction of cytokeratin from the human submandibular gland and its electrophoretic analysis. Res Commun Mol Pathol Pharmacol 101:115-26 (1998). Read more (PubMed: 9821208) »

See all 3 Publications for this product

Product Wall

;anticorps ab106166 est à €370 et a une concentration de 0.1mg/ml. Lot 1408490 est en stock en Grande Bretagne. Le control isotype pour cet anticorps est ab91358 à €350. Il est à une concentration de 0.025 mg/ml et est en...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"