Not tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2.
Highest expression in prostate, testis and colon.
Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. Contains 1 CRIB domain. Contains 1 protein kinase domain.
Autophosphorylated on serine residues when activated by CDC42/p21. Phosphorylated on tyrosine residues upon stimulation of FGFR2.
P21 protein (Cdc42/Rac) activated kinase 4 antibody
p21(CDKN1A) activated kinase 4 antibody
p21-activated kinase 4 antibody
PAK 4 antibody
Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs antibody
Serine threonine kinase PAK 4 antibody
Serine/threonine protein kinase PAK 4 antibody
Serine/threonine protein kinase PAK4 antibody
Serine/threonine-protein kinase PAK 4 antibody
Western blot - Anti-PAK4 antibody (ab17974)
Predicted band size : 64 kDa
Detection of Human PAK4 by Western Blot following Immunoprecipitation. Samples: Whole cell lysate from HeLa (5 x 106) or Jurkat (25 x 106) cells. Antibody: Affinity purified rabbit anti-PAK4 (ab17974) used at 4 mcg for IP and at 1 mcg/ml for Western Blot. Detection: Chemiluminescence.