製品の概要

  • 製品名Anti-PAK4 antibody
    PAK4 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PAK4
  • アプリケーション適用あり: IP, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rabbit, Guinea pig, Dog, Pig, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide representing a portion of human p21(CDKN1A) activated kinase 4 encoded within exon 4 (Locuslink ID 10298).

  • ポジティブ・コントロール
    • Whole cell lysate of Hela or Jurkat cells.

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab17974 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IP
WB
  • 追加情報
    IP: 1 to 4 mcg/mg lysate
    WB: 1/1000 - 1/5000. Predicted molecular weight: 64 kDa.

    Not tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Activates the JNK pathway. Plays a role in the reorganization of the actin cytoskeleton and in the formation of filopodia. Phosphorylates and inactivates the protein phosphatase SSH1, leading to increased inhibitory phosphorylation of the actin binding/depolymerizing factor cofilin. Decreased cofilin activity may lead to stabilization of actin filaments. Phosphorylates ARHGEF2.
    • 組織特異性Highest expression in prostate, testis and colon.
    • 配列類似性Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily.
      Contains 1 CRIB domain.
      Contains 1 protein kinase domain.
    • 翻訳後修飾Autophosphorylated on serine residues when activated by CDC42/p21.
      Phosphorylated on tyrosine residues upon stimulation of FGFR2.
    • Information by UniProt
    • 参照データベース
    • 別名
      • KIAA1142 antibody
      • p21 activated kinase 4 antibody
      • p21 Cdc42/Rac1-actiated kinase 4 antibody
      • P21 protein (Cdc42/Rac) activated kinase 4 antibody
      • p21(CDKN1A) activated kinase 4 antibody
      • p21-activated kinase 4 antibody
      • PAK 4 antibody
      • PAK-4 antibody
      • Pak4 antibody
      • PAK4_HUMAN antibody
      • Protein kinase related to S.cerevisiae STE20 effector for Cdc42Hs antibody
      • Serine threonine kinase PAK 4 antibody
      • Serine/threonine protein kinase PAK 4 antibody
      • Serine/threonine protein kinase PAK4 antibody
      • Serine/threonine-protein kinase PAK 4 antibody
      see all

    Anti-PAK4 antibody 画像



    • Predicted band size : 64 kDa


      Detection of Human PAK4 by Western Blot following Immunoprecipitation. Samples: Whole cell lysate from HeLa (5 x 106) or Jurkat (25 x 106) cells. Antibody: Affinity purified rabbit anti-PAK4 (ab17974) used at 4 mcg for IP and at 1 mcg/ml for Western Blot. Detection: Chemiluminescence.

    Anti-PAK4 antibody (ab17974) 使用論文

    ab17974 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab17974.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"