Anti-PAF1/PD2 抗体 (ab70638)
Key features and details
- Rabbit polyclonal to PAF1/PD2
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-PAF1/PD2 antibody
PAF1/PD2 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PAF1/PD2 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide corresponding to Human PAF1/PD2.
Database link: Q9NUU9 -
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.1% Sodium azide
Constituents: 1.815% Tris, 1.764% Sodium citrate, 0.021% PBS -
Concentration information loading...
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精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab70638の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
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特記事項 |
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IHC-P
1/500 - 1/2000. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol. |
ターゲット情報
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機能
The mammalian PAF1 complex is a multifunctional complex. The PAF1 complex interacts with RNA polymerase II and may be involved in both initiation and elongation, and in histone methylation and RNA processing. Has oncogenic activity in vivo and in vitro. -
配列類似性
Belongs to the PAF1 family. -
細胞内局在
Nucleus. Punctuate distribution throughout the nucleus except in nucleoli and the perinuclear chromatin. - Information by UniProt
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参照データベース
- Entrez Gene: 54623 Human
- Entrez Gene: 54624 Mouse
- Omim: 610506 Human
- SwissProt: Q8N7H5 Human
- SwissProt: Q8K2T8 Mouse
- Unigene: 466714 Human
- Unigene: 7916 Mouse
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別名
- F23149 1 antibody
- FLJ11123 antibody
- hPAF1 antibody
see all
画像
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human breast teratoma tissue labelling PAF1/PD2 with ab70638 at 1/1000 (1µg/ml). Detection: DAB.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse teratoma tissue labelling PAF1/PD2 with ab70638 at 1/1000 (1µg/ml). Detection: DAB.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (1)
ab70638 は 1 報の論文で使用されています。
- Rauth S et al. SUMO Modification of PAF1/PD2 Enables PML Interaction and Promotes Radiation Resistance in Pancreatic Ductal Adenocarcinoma. Mol Cell Biol 41:e0013521 (2021). PubMed: 34570619