Anti-PADI3 / PAD3 抗体 (ab50246)
Key features and details
- Rabbit polyclonal to PADI3 / PAD3
- Suitable for: ELISA, IP, WB
- Reacts with: Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-PADI3 / PAD3 antibody
PADI3 / PAD3 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PADI3 / PAD3 -
由来種
Rabbit -
特異性
This antibody reacts specifically with the 75kDa PADI3 / PAD3 protein. It shows no cross reactivity with the other isoforms. -
アプリケーション
適用あり: ELISA, IP, WBmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat -
免疫原
A 15 amino acid residue synthetic peptide derived from the N-terminal domain of human PADI3/ PAD3.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
Constituent: Whole serum -
Concentration information loading...
-
精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab50246の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ELISA |
Use at an assay dependent concentration.
|
|
IP |
Use at an assay dependent concentration.
|
|
WB | (1) |
Use at an assay dependent concentration.
|
特記事項 |
---|
ELISA
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
WB
Use at an assay dependent concentration. |
ターゲット情報
-
機能
Catalyzes the deimination of arginine residues of proteins. -
組織特異性
Hair follicles, and epidermis at very low levels. -
配列類似性
Belongs to the protein arginine deiminase family. -
細胞内局在
Cytoplasm. - Information by UniProt
-
参照データベース
- Entrez Gene: 51702 Human
- Entrez Gene: 18601 Mouse
- Entrez Gene: 29520 Rat
- Omim: 606755 Human
- SwissProt: Q9ULW8 Human
- SwissProt: Q9Z184 Mouse
- SwissProt: P70708 Rat
- Unigene: 149195 Human
see all -
別名
- PADI3 antibody
- PADI3_HUMAN antibody
- PDI3 antibody
see all
プロトコール
データシートおよび資料
-
Datasheet download
参考文献 (17)
ab50246 は 17 報の論文で使用されています。
- Pasquero S et al. Novel antiviral activity of PAD inhibitors against human beta-coronaviruses HCoV-OC43 and SARS-CoV-2. Antiviral Res 200:105278 (2022). PubMed: 35288208
- D'Alessio S et al. Acute Hypoxia Alters Extracellular Vesicle Signatures and the Brain Citrullinome of Naked Mole-Rats (Heterocephalus glaber). Int J Mol Sci 23:N/A (2022). PubMed: 35563075
- Inal JM et al. A Pilot Study on Peptidylarginine Deiminases and Protein Deimination in Animal Cancers across Vertebrate Species. Int J Mol Sci 23:N/A (2022). PubMed: 35955829
- Sawata M et al. Autocitrullination and Changes in the Activity of Peptidylarginine Deiminase 3 Induced by High Ca2+ Concentrations. ACS Omega 7:28378-28387 (2022). PubMed: 35990454
- Uysal-Onganer P et al. Peptidylarginine Deiminase Inhibitor Application, Using Cl-Amidine, PAD2, PAD3 and PAD4 Isozyme-Specific Inhibitors in Pancreatic Cancer Cells, Reveals Roles for PAD2 and PAD3 in Cancer Invasion and Modulation of Extracellular Vesicle Signatures. Int J Mol Sci 22:N/A (2021). PubMed: 33573274