製品の概要

製品の詳細

  • 由来
    Synthetic

関連製品

特性

Our Abpromise guarantee covers the use of ab109076 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 精製度
    70 - 90% by HPLC.

  • 備考

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

前処理および保存

  • 保存方法および安定性

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

関連情報

  • 別名
    • ADCYAP1 R1
    • ADCYAP1R 1
    • ADCYAP1R1
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I
    • PAC 1
    • PAC1
    • PAC1R
    • PACAP receptor 1
    • PACAP type I receptor
    • PACAP-R-1
    • PACAP-R1
    • PACAP1 R
    • PACAPR
    • PACAPRI
    • PACR_HUMAN
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop
    • Pituitary adenylate cyclase activating polypeptide receptor
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for
    • Pituitary adenylate cyclase-activating polypeptide type I receptor
    • pvr1
    see all
  • 機能
    This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
  • 組織特異性
    Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
  • 配列類似性
    Belongs to the G-protein coupled receptor 2 family.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt

参考文献

ab109076 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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