Anti-PACAP receptor/ADCYAP1R1 抗体 (ab28670)
Key features and details
- Rabbit polyclonal to PACAP receptor/ADCYAP1R1
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
製品の概要
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製品名
Anti-PACAP receptor/ADCYAP1R1 antibody
PACAP receptor/ADCYAP1R1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to PACAP receptor/ADCYAP1R1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Human
交差が予測される動物種: Mouse, Rat, Cow -
免疫原
Synthetic peptide corresponding to Human PACAP receptor/ADCYAP1R1 aa 400-500 conjugated to keyhole limpet haemocyanin.
Database link: P41586 -
ポジティブ・コントロール
- IHC-P: Human myenteric ganglia cells of the small intestine.
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
Preservative: 0.05% Sodium azide
Constituent: Whole serum -
Concentration information loading...
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精製度
Whole antiserum -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab28670の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-P |
1/500.
|
特記事項 |
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IHC-P
1/500. |
ターゲット情報
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機能
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract. -
組織特異性
Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta. -
配列類似性
Belongs to the G-protein coupled receptor 2 family. -
細胞内局在
Cell membrane. - Information by UniProt
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参照データベース
- Entrez Gene: 117 Human
- Entrez Gene: 11517 Mouse
- Entrez Gene: 24167 Rat
- Omim: 102981 Human
- SwissProt: P41586 Human
- SwissProt: P70205 Mouse
- SwissProt: P32215 Rat
- Unigene: 377783 Human
see all -
別名
- ADCYAP1 R1 antibody
- ADCYAP1R 1 antibody
- ADCYAP1R1 antibody
see all
画像
データシートおよび資料
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Datasheet download
参考文献 (4)
ab28670 は 4 報の論文で使用されています。
- Frausto RF et al. ZEB1 insufficiency causes corneal endothelial cell state transition and altered cellular processing. PLoS One 14:e0218279 (2019). PubMed: 31194824
- Frederiksen SD et al. Expression of Pituitary Adenylate Cyclase-activating Peptide, Calcitonin Gene-related Peptide and Headache Targets in the Trigeminal Ganglia of Rats and Humans. Neuroscience 393:319-332 (2018). PubMed: 30336190
- Rice FL et al. Anatomy and immunochemical characterization of the non-arterial peptidergic diffuse dural innervation of the rat and Rhesus monkey: Implications for functional regulation and treatment in migraine. Cephalalgia 37:1350-1372 (2017). PubMed: 27852962
- Ortner A et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles. J Drug Target 18:457-67 (2010). ICC ; Human . PubMed: 20050817