製品の概要

  • 製品名Anti-PACAP receptor antibody
    PACAP receptor 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to PACAP receptor
  • アプリケーション適用あり: IHC-P, ICC, WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Cow
  • 免疫原

    Synthetic peptide:

    LSKSSSQIRMSGLPADNLAT

    conjugated to KLH, corresponding to amino acids 506-525 of Human PACAP receptor.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab28670 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P 1/500.
ICC 1/1000.
WB 1/1000. Detects a band of approximately 40-60 kDa (predicted molecular weight: 55 kDa).

ターゲット情報

  • 機能This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
  • 組織特異性Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
  • 配列類似性Belongs to the G-protein coupled receptor 2 family.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADCYAP1 R1 antibody
    • ADCYAP1R 1 antibody
    • ADCYAP1R1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type 1 antibody
    • Adenylate cyclase activating polypeptide 1 (pituitary) receptor type I antibody
    • PAC 1 antibody
    • PAC1 antibody
    • PAC1R antibody
    • PACAP receptor 1 antibody
    • PACAP type I receptor antibody
    • PACAP-R-1 antibody
    • PACAP-R1 antibody
    • PACAP1 R antibody
    • PACAPR antibody
    • PACAPRI antibody
    • PACR_HUMAN antibody
    • Pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop antibody
    • Pituitary adenylate cyclase activating polypeptide receptor antibody
    • Pituitary adenylate cyclase activating polypeptide type I receptor precursor antibody
    • Pituitary adenylate cyclase-activating polypeptide 1, receptor for antibody
    • Pituitary adenylate cyclase-activating polypeptide type I receptor antibody
    • pvr1 antibody
    see all

Anti-PACAP receptor antibody 画像

  • ab28670 staining Human PACAP receptor in human myenteric ganglia cells of the small intestine by immunohistochemistry using paraffin embedded tissue.

Anti-PACAP receptor antibody (ab28670) 使用論文

This product has been referenced in:
  • Ortner A  et al. VPAC receptor mediated tumor cell targeting by protamine based nanoparticles. J Drug Target 18:457-67 (2010). ICC ; Human . Read more (PubMed: 20050817) »

See 1 Publication for this product

Product Wall

Application Western blot
Loading amount 25 µg
Gel Running Conditions Reduced Denaturing (10% Gel)
Sample Mouse Tissue lysate - whole (Dorsal Hippocampal Tissue)
Specification Dorsal Hippocampal Tissue
Blocking step I-Block as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 0.2% · Temperature: 20°C
Username

Abcam user community

Verified customer

投稿 Oct 14 2013

Thank you for your reply.

Because ab8901 has been validated for use in rat and RIA, it will be guaranteed for your experiments and would not qualify for the testing discount program. I would be happy to manually submit your Abreview and award...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"