Rabbit polyclonal to P70 S6 Kinase beta (phospho S371)
ab60947 detects endogenous levels of P70 S6 Kinase beta only when phosphorylated at serine 371.
Synthetic phosphopeptide derived from human P70 S6 Kinase beta around the phosphorylation site of serine 371 (V-D-S
Human breast carcinoma tissue.
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 50% Glycerol, PBS (without Mg 2+ and Ca 2+), 150mM Sodium chloride, pH 7.4
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Immunogen affinity purified
ab60947 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 23874880
1/50 - 1/100.
1/50 - 1/100.
Phosphorylates specifically ribosomal protein S6.
Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily.
Contains 1 AGC-kinase C-terminal domain. Contains 1 protein kinase domain.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
70 kDa ribosomal protein S6 kinase 2 antibody
EC 126.96.36.199 antibody
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