製品の概要

  • 製品名Anti-P5CS antibody
    P5CS 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to P5CS
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Zebrafish
  • 免疫原

    Synthetic peptide within residues: VIRHVRSWSN IPFITVPLSR THGKSFAHRS ELKHAKRIVV KLGSAVVTRG, corresponding to N terminal amino acids 36-85 of Human P5CS (NP_001017423).

  • ポジティブ・コントロール
    • 721_B cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab90872 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 87 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • パスウェイAmino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.
    Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.
  • 関連疾患Defects in ALDH18A1 are the cause of mental retardation-joint hypermobility-skin laxity with or without metabolic abnormalities (MRJHSL) [MIM:612652]. Clinical manifestations include microcephaly, progressive neurologic dysfunction, mental retardation, progeroid appearance, joint hypermobility, skin laxity and hyperelasticity, cataracts. Some patients manifest metabolic disturbances such as hyperammonemia, hypoornithinemia, hypocitrullinemia, hypoargininemia and hypoprolinemia.
  • 配列類似性In the N-terminal section; belongs to the glutamate 5-kinase family.
    In the C-terminal section; belongs to the gamma-glutamyl phosphate reductase family.
  • 細胞内局在Mitochondrion inner membrane.
  • Information by UniProt
  • 参照データベース
  • 製品の状態P5CS catalyzes the ATP- and NADPH-dependent conversion of L-glutamate to glutamic gamma-semialdehyde, which is the metabolic precursor for proline biosynthesis. There are 2 isoforms produced by alternative splicing.
  • 別名
    • 2810433K04Rik antibody
    • AI429789 antibody
    • Aldehyde dehydrogenase 18 family member A1 antibody
    • Aldehyde dehydrogenase 18A1 antibody
    • Aldehyde dehydrogenase family 18 member A1 antibody
    • ALDH18A1 antibody
    • Delta 1 pyrroline 5 carboxylate synthetase antibody
    • Delta1 pyrroline 5 carboxlate synthetase antibody
    • Gamma-glutamyl kinase antibody
    • Gamma-glutamyl phosphate reductase antibody
    • GK antibody
    • Glutamate-5-semialdehyde dehydrogenase antibody
    • Glutamyl-gamma-semialdehyde dehydrogenase antibody
    • GPR antibody
    • GSAS antibody
    • MGC117316 antibody
    • MGC32233 antibody
    • P5CS antibody
    • P5CS_HUMAN antibody
    • PYCS antibody
    • Pyrroline 5 carboxylate synthetase (glutamate gamma semialdehyde synthetase) antibody
    see all

Anti-P5CS antibody 画像

  • Anti-P5CS antibody (ab90872) at 1 µg/ml + 721_B cell lysate at 10 µg

    Secondary
    anti-Rabbit IgG HRP at 1/50000 dilution

    Predicted band size : 87 kDa

Anti-P5CS antibody (ab90872) 使用論文

ab90872 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"