Anti-p57 Kip2 (phospho T310) 抗体 (ab61064)


  • 製品名Anti-p57 Kip2 (phospho T310) antibody
    p57 Kip2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to p57 Kip2 (phospho T310)
  • 特異性Ab61064 detects endogenous levels of p57 Kip2 only when phosphorylated at threonine 310.
  • アプリケーション適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Mouse
  • 免疫原

    Synthesized phosphopeptide derived from human p57 Kip2 around the phosphorylation site of threonine 310(E-Q-TP-P-R).

  • ポジティブ・コントロール
    • Human placenta tissue


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab61064 was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation site.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野


Our Abpromise guarantee covers the use of ab61064 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Predicted molecular weight: 32 kDa.
ELISA 1/5000.
IHC-P 1/50 - 1/100.


  • 機能Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
  • 組織特異性Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. High levels are seen in the placenta while low levels are seen in the liver.
  • 関連疾患Defects in CDKN1C are a cause of Beckwith-Wiedemann syndrome (BWS) [MIM:130650]. BWS is a genetically heterogeneous disorder characterized by anterior abdominal wall defects including exomphalos (omphalocele), pre- and postnatal overgrowth, and macroglossia. Additional less frequent complications include specific developmental defects and a predisposition to embryonal tumors.
    Note=Defects in CDKN1C are involved in tumor formation.
  • 配列類似性Belongs to the CDI family.
  • 細胞内局在Nucleus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Beckwith Wiedemann syndrome antibody
    • BWCR antibody
    • BWS antibody
    • CDKI antibody
    • CDKN 1C antibody
    • CDKN1C antibody
    • CDN1C_HUMAN antibody
    • Cyclin dependent kinase inhibitor 1C antibody
    • Cyclin dependent kinase inhibitor p57 antibody
    • Cyclin-dependent kinase inhibitor 1C antibody
    • Cyclin-dependent kinase inhibitor p57 antibody
    • KIP 2 antibody
    • KIP2 antibody
    • p57 antibody
    • p57 Kip 2 antibody
    • p57KIP2 antibody
    • WBS antibody
    see all

Anti-p57 Kip2 (phospho T310) antibody 画像

  • Immunohistochemistry analysis of paraffin-embedded human placenta tissue using ab61064 at 1/50-1/100 dilution with or without addition of Phospho-peptide.

  • Predicted band size : 32 kDa

    Western Blot analysis of K562 cell lysates labeling p57 Kip2 (phospho T310) with ab61064 at 0.01U/ml for 15 minutes. The lane on the right is blocked with the phospho peptide.

Anti-p57 Kip2 (phospho T310) antibody (ab61064) 使用論文

ab61064 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab61064.
Please use the links above to contact us or submit feedback about this product.