製品の概要

  • 製品名Anti-P2Y12 antibody
    P2Y12 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to P2Y12
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Rat
    交差が予測される動物種: Mouse
  • 免疫原

    Synthetic peptide corresponding to Rat P2Y12 aa 1-100 conjugated to keyhole limpet haemocyanin.
    Database link: Q9EPX4
    (Peptide available as ab115243)

  • ポジティブ・コントロール
    • This antibody gave a positive signal in Rat brain tissue lysate.

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーpH: 7.40
    Preservative: 0.02% Sodium azide
    Constituent: PBS
    Note: Batches of this product that have a concentration < 1mg/ml may have BSA added as a stabilising agent. If you would like information about the formulation of a specific lot, please contact our scientific support team who will be happy to help.
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab102672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Detects a band of approximately 44 kDa (predicted molecular weight: 39 kDa).

ターゲット情報

  • 機能Receptor for ADP and ATP coupled to G-proteins that inhibit the adenylyl cyclase second messenger system. Not activated by UDP and UTP. Involved in platelets aggregation.
  • 組織特異性Highly expressed in the platelets, lower levels in the brain. Lowest levels in the lung, appendix, pituitary and adrenal gland. Expressed in the spinal cord and in the fetal brain.
  • 関連疾患Defects in P2RY12 are the cause of P2RY12 deficiency (P2RY12D) [MIM:609821]. It is a condition characterized by severe impairment of platelet response to ADP and abnormal bleeding marked by excessive posttraumatic and postsurgical blood loss.
  • 配列類似性Belongs to the G-protein coupled receptor 1 family.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ADP glucose receptor antibody
    • ADP-glucose receptor antibody
    • ADPG R antibody
    • ADPG-R antibody
    • ADPGR antibody
    • BDPLT8 antibody
    • G protein coupled receptor SP1999 antibody
    • Gi coupled ADP receptor HORK 3 antibody
    • Gi coupled ADP receptor HORK3 antibody
    • HORK 3 antibody
    • HORK3 antibody
    • P2RY 12 antibody
    • P2RY12 antibody
    • P2T(AC) antibody
    • P2Y 12 antibody
    • P2Y purinoceptor 12 antibody
    • P2Y(12)R antibody
    • P2Y(AC) antibody
    • P2Y(ADP) antibody
    • P2Y(cyc) antibody
    • P2Y12 antibody
    • P2Y12 platelet ADP receptor antibody
    • P2Y12_HUMAN antibody
    • Platelet ADP receptor antibody
    • Purinergic receptor P2RY12 antibody
    • Purinergic receptor P2Y G protein coupled 12 antibody
    • Purinergic receptor P2Y12 antibody
    • Putative G protein coupled receptor antibody
    • SP 1999 antibody
    • SP1999 antibody
    see all

Anti-P2Y12 antibody 画像

  • Anti-P2Y12 antibody (ab102672) at 1 µg/ml + Brain (Rat) Tissue Lysate (ab7942) at 20 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Predicted band size : 39 kDa
    Observed band size : 44 kDa (why is the actual band size different from the predicted?)


    Exposure time : 16 minutes

Anti-P2Y12 antibody (ab102672) 使用論文

ab102672 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab102672.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"