製品の概要

  • 製品名Anti-P2X2 antibody
    P2X2 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to P2X2
  • アプリケーション適用あり: WB, IHC-Fr, ICC, IHC-Pmore details
  • 種交差性
    交差種: Rat, Human
    交差が予測される動物種: Mouse, Guinea pig, Non Human Primates
  • 免疫原

    Synthetic peptide:

    DSTSTDPKGLAQL

    , corresponding to amino acids 460-472 of Rat P2X2.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab10266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 47,8 kDa.
IHC-Fr 1/1000.
ICC 1/1000.
IHC-P Use at an assay dependent concentration. PubMed: 21969132

ターゲット情報

  • 機能Ion channel gated by extracellular ATP involved in a variety of cellular responses, such as excitatory postsynaptic responses in sensory neurons, neuromuscular junctions (NMJ) formation, hearing, perception of taste and peristalsis. In the inner ear, regulates sound transduction and auditory neurotransmission, outer hair cell electromotility, inner ear gap junctions, and K(+) recycling. Mediates synaptic transmission between neurons and from neurons to smooth muscle.
  • 関連疾患Deafness, autosomal dominant, 41
  • 配列類似性Belongs to the P2X receptor family.
  • 細胞内局在Cell membrane. Localizes to the apical membranes of hair cells in the organ of Corti.
  • Information by UniProt
  • 参照データベース
  • 製品の状態There are 7 isoforms produced by alternative splicing.
  • 別名
    • ATP receptor antibody
    • MGC129601 antibody
    • P2RX 2 antibody
    • P2RX2 antibody
    • P2RX2_HUMAN antibody
    • P2X purinoceptor 2 antibody
    • P2X Receptor subunit 2 antibody
    • P2X2 antibody
    • P2X2a antibody
    • Purinergic receptor antibody
    • Purinergic receptor P2X ligand gated ion channel 2 antibody
    • Purinergic receptor P2X2 isoform A antibody
    • Purinergic receptor P2X2 isoform B antibody
    • Purinergic receptor P2X2 isoform C antibody
    • Purinergic receptor P2X2 isoform D antibody
    • Purinergic receptor P2X2 isoform H antibody
    • Purinergic receptor P2X2 isoform I antibody
    see all

Anti-P2X2 antibody 画像

  • ab10266, at a dilution of 1/1000, staining P2X2 in rat brain stem by Immunohistochemistry (PFA perfusion fixed frozen sections).

Anti-P2X2 antibody (ab10266) 使用論文

This product has been referenced in:
  • Kútna V  et al. Enigmatic cerebrospinal fluid-contacting neurons arise even after the termination of neurogenesis in the rat spinal cord during embryonic development and retain their immature-like characteristics until adulthood. Acta Histochem N/A:N/A (2013). Read more (PubMed: 24063862) »
  • Wu T  et al. Functional expression of P2X4 receptor in capillary endothelial cells of the cochlear spiral ligament and its role in regulating the capillary diameter. Am J Physiol Heart Circ Physiol 301:H69-78 (2011). Read more (PubMed: 21460192) »

See all 3 Publications for this product

Product Wall

Thank you for your inquiry.

As you correctly suspected, we do not know the concentration of the antibody.

Antibody concentration is usually measured by measuring the protein content. Since there are many different proteins in whole ...

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Thank you for your inquiry. To our knowledge, ab10266 has not yet been tested in flow cytometry. It is possible that this product may be suitable for your experiment since it has been successfully used in ICC, but we don't have any data regarding its ...

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Thank you for your enquiry. Antibodies ab10262 and ab10266 are raised against the same peptide which, according to the map found at the link to the SwissProt entry with accession number P49653, is found on a cytoplasmic domain of the protein. I h...

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Thank you for your enquiry and for your patience. The epitopes are intracellular for both ab10266 and ab10267. So unfortunately, they will not suit your needs. If you have any more questions, please contact us again.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"