Anti-p15 INK4b 抗体 [DCS-114] (ab44891)
Key features and details
- Mouse monoclonal [DCS-114] to p15 INK4b
- Suitable for: ELISA, ICC, IP, ICC/IF, IHC
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-p15 INK4b antibody [DCS-114]
p15 INK4b 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [DCS-114] to p15 INK4b -
由来種
Mouse -
アプリケーション
適用あり: ELISA, ICC, IP, ICC/IF, IHCmore details
適用なし: WB -
種交差性
交差種: Human
非交差種: Mouse, Rat -
免疫原
Recombinant full length protein corresponding to Human p15 INK4b.
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ポジティブ・コントロール
- Ls174T cells
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
バッファー
pH: 7.40
Preservative: 0.1% Sodium azide
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
ポリ/モノ
モノクローナル -
クローン名
DCS-114 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab44891の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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ELISA |
Use at an assay dependent concentration.
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ICC |
Use at an assay dependent concentration.
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IF |
Use at an assay dependent concentration.
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IP |
Use at an assay dependent concentration.
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ICC/IF |
Use at an assay dependent concentration.
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IHC |
Use at an assay dependent concentration.
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特記事項 |
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ELISA
Use at an assay dependent concentration. |
ICC
Use at an assay dependent concentration. |
IF
Use at an assay dependent concentration. |
IP
Use at an assay dependent concentration. |
ICC/IF
Use at an assay dependent concentration. |
IHC
Use at an assay dependent concentration. |
ターゲット情報
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機能
Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest. -
配列類似性
Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.
Contains 4 ANK repeats. - Information by UniProt
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参照データベース
- Entrez Gene: 1030 Human
- Omim: 600431 Human
- SwissProt: P42772 Human
- Unigene: 72901 Human
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別名
- CDK inhibitory protein antibody
- CDK4B Inhibitor antibody
- Cdkn2b antibody
see all
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (4)
ab44891 は 4 報の論文で使用されています。
- Gray-Bablin J et al. Lovastatin induction of cyclin-dependent kinase inhibitors in human breast cells occurs in a cell cycle-independent fashion. Cancer Res 57:604-9 (1997). PubMed: 9044834
- Naumann M et al. Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors. Gastroenterology 110:1215-24 (1996). PubMed: 8613012
- Saxena A et al. Abnormalities of p16, p15 and CDK4 genes in recurrent malignant astrocytomas. Oncogene 13:661-4 (1996). PubMed: 8760309
- Takeuchi S et al. Analysis of a family of cyclin-dependent kinase inhibitors: p15/MTS2/INK4B, p16/MTS1/INK4A, and p18 genes in acute lymphoblastic leukemia of childhood. Blood 86:755-60 (1995). PubMed: 7606004