Anti-P Glycoprotein 抗体 [JSB-1], prediluted (ab51893)


  • 製品名Anti-P Glycoprotein antibody [JSB-1], prediluted
    P Glycoprotein 一次抗体 製品一覧
  • 製品の詳細
    Mouse monoclonal [JSB-1] to P Glycoprotein, prediluted
  • アプリケーション適用あり: IHC-Pmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Chinese hamster ovary cell line (CHrC5) expressing Human MDR (170-180 kDa Glykoprotein)

  • ポジティブ・コントロール
    • Human liver or renal carcinoma.



Our Abpromise guarantee covers the use of ab51893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
  • 追加情報IHC-P: we recommend using 100µl working solution per test and incubating the antibody for 60 mins at room temperature. Antigen unmasking required for paraffin embedded sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells.
    • 組織特異性Expressed in liver, kidney, small intestine and brain.
    • 関連疾患Genetic variations in ABCB1 are associated with susceptibility to inflammatory bowel disease type 13 (IBD13) [MIM:612244]. Inflammatory bowel disease is characterized by a chronic relapsing intestinal inflammation. It is subdivided into Crohn disease and ulcerative colitis phenotypes. Crohn disease may involve any part of the gastrointestinal tract, but most frequently the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. Crohn disease and ulcerative colitis are commonly classified as autoimmune diseases.
    • 配列類似性Belongs to the ABC transporter superfamily. ABCB family. Multidrug resistance exporter (TC 3.A.1.201) subfamily.
      Contains 2 ABC transmembrane type-1 domains.
      Contains 2 ABC transporter domains.
    • 細胞内局在Membrane.
    • Information by UniProt
    • 参照データベース
    • 別名
      • ABC20 antibody
      • ABCB1 antibody
      • ATP binding cassette, sub family B (MDR/TAP), member 1 antibody
      • ATP-binding cassette sub-family B member 1 antibody
      • CD243 antibody
      • CLCS antibody
      • Colchicin sensitivity antibody
      • Doxorubicin resistance antibody
      • GP170 antibody
      • MDR1 antibody
      • MDR1_HUMAN antibody
      • Multidrug resistance 1 antibody
      • Multidrug resistance protein 1 antibody
      • P glycoprotein 1 antibody
      • P gp antibody
      • P-glycoprotein 1 antibody
      • PGY1 antibody
      see all

    Anti-P Glycoprotein antibody [JSB-1], prediluted (ab51893) 使用論文

    ab51893 has not yet been referenced specifically in any publications.

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