製品の概要

  • 製品名Anti-P cadherin antibody
    P cadherin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to P cadherin
  • アプリケーション適用あり: WB, IHC-P, ICCmore details
  • 種交差性
    交差種: Recombinant Fragment
    交差が予測される動物種: Human
  • 免疫原

    Synthetic peptide corresponding to a sequence at the middle region of human P-Cadherin, different from the mouse and rat sequence by one amino acid.

  • ポジティブ・コントロール
    • recombinant Human P cadherin

法規制情報

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファーPreservatives: 0.02% Sodium azide, 0.01% Thimerosal (merthiolate)
    Constituents: 0.05% BSA, Sodium chloride, 0.01% Monobasic dihydrogen sodium phosphate
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab111010 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 22 kDa.
IHC-P Use a concentration of 1 µg/ml. Perform heat mediated antigen retrieval before commencing with IHC staining protocol.
ICC Use a concentration of 1 µg/ml.

ターゲット情報

  • 機能Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
  • 組織特異性Expressed in some normal epithelial tissues and in some carcinoma cell lines.
  • 関連疾患Defects in CDH3 are the cause of hypotrichosis with juvenile macular dystrophy (HJMD) [MIM:601553]. HJMD is a rare autosomal recessive disorder characterized by early hair loss heralding severe degenerative changes of the retinal macula and culminating in blindness during the second to third decade of life.
    Defects in CDH3 are the cause of ectodermal dysplasia with ectrodactyly and macular dystrophy (EEM) [MIM:225280]; also known as EEM syndrome, Albrectsen-Svendsen syndrome or Ohdo-Hirayama-Terawaki syndrome. Ectodermal dysplasia defines a heterogeneous group of disorders due to abnormal development of two or more ectodermal structures. EEM is an autosomal recessive condition characterized by features of ectodermal dysplasia such as sparse eyebrows and scalp hair, and selective tooth agenesis associated with macular dystrophy and ectrodactyly.
  • 配列類似性Contains 5 cadherin domains.
  • 細胞内局在Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • CADH3_HUMAN antibody
    • Cadherin 3 antibody
    • Cadherin 3 precursor antibody
    • Cadherin 3 type 1 antibody
    • Cadherin-3 antibody
    • Cadp antibody
    • Calcium dependent adhesion protein placental antibody
    • CDH 3 antibody
    • CDH3 antibody
    • CDH3 protein antibody
    • CDHP antibody
    • HJMD antibody
    • P cadherin (placental) antibody
    • P-cadherin antibody
    • PCAD antibody
    • Placental cadherin antibody
    see all

Anti-P cadherin antibody 画像

  • All lanes : Anti-P cadherin antibody (ab111010) at 1 µg/ml

    Lane 1 : Recombinant P cadherin protein at 0.01 µg
    Lane 2 : Recombinant P cadherin protein at 0.005 µg
    Lane 3 : Recombinant P cadherin protein at 0.0025 µg
    Lane 4 : MK (55KD)


    Predicted band size : 22 kDa

Anti-P cadherin antibody (ab111010) 使用論文

ab111010 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab111010.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"