Anti-Ovine MHC Class II DR 抗体 [37.68] (ab34007)


  • 製品名Anti-Ovine MHC Class II DR antibody [37.68]
  • 製品の詳細
    Mouse monoclonal [37.68] to Ovine MHC Class II DR
  • アプリケーション適用あり: Flow Cyt, IP, IHC-Frmore details
  • 種交差性
    交差種: Sheep, Goat, Cow, Human
  • 免疫原

    Splenocytes from ATL mice


  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.09% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 精製度Protein G purified
  • 特記事項(精製)Purified from tissue culture supernatant.
  • ポリ/モノモノクローナル
  • クローン名37.68
  • アイソタイプIgG2a
  • 研究分野


Our Abpromise guarantee covers the use of ab34007 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
Flow Cyt
  • 追加情報Flow Cyt: Use 1/50 - 1/200, or 10µl of the suggested working dilution to label 106 cells in 100µl.
    IHC-Fr: Use at an assay dependent dilution.
    IP: Use at an assay dependent dilution.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 関連性Three subregions of the Major Histocompatibility Complex (MHC), DP, DQ and DR, determine class II molecules, which are essential in the cellular recognition interactions involved in the generation of an immune response. These molecules display processed antigens from virally-infected or transformed cells. Class-II-positive cells (antigen-presenting cells) can take up antigens from outside by endocytosis, degrade them into small peptides, and re-export the peptides (now bound to MHC class II protein) to the cell surface. These peptide-MHC class II complexes can then be recognized by specific CD4+ lymphocytes. Several class II antigens are also associated with disease states. The extremely high polymorphism of MHC class II transmembrane heterodimers is due to a few hypervariable segments present in the most external domain of their alpha and beta chains. The alpha chain of MHC-DR is not polymorphic, whereas the beta chain is highly so. Some changes in amino acid sequence are critical in disease susceptibility associations as well as the ability to present processed antigens to T cells.
    • 細胞内局在Cell Membrane
    • 別名
      • DR alpha chain antibody
      • DR beta 5 antibody
      • HLA class II histocompatibility antigen antibody
      • HLA DRA antibody
      • HLA DRB1 antibody
      • MHC class II antigen DRA antibody
      see all

    Anti-Ovine MHC Class II DR antibody [37.68] (ab34007) 使用論文

    ab34007 has not yet been referenced specifically in any publications.

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