Ouabain octahydrate (ab120748)

製品の概要

• 製品名
  Ouabain octahydrate
• 製品の詳細
  Na⁺/K⁺ ATPase inhibitor
• 生理活性の詳細
  Na⁺/K⁺ ATPase inhibitor (K_i = 30 μM). Cardiac glycoside. Stimulates activity at low nanomolar concentrations in rats. Improves cardiac function in myocardial infarction rats. Centrally active following oral administration.
• 精製度
  > 97%
• 特記事項

  It has been reported that an aqueous solution of this material stored overnight in a borosilicate glass vial leads to the formation of ouabain-borate complexes.
  It is therefore recommended that this material is stored in a plastic vial and any contact with borosilicate glass is minimised.

製品の特性

• 体系名
  (1β,3β,5β,11α)-3-[(6-Deoxy-α-L-mannopyranosyl)oxy]-1,5,11,14,19-pentahydroxycard-20(22)-enolide
• 分子量
  728.78
• 構造式
  
• 分子式
  C₂₉H₄₄O₁₂.8H₂O
• CAS 番号
  11018-89-6
• 保存方法
  Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
• 溶解性
  Soluble in DMSO to 100 mM, in ethanol to 10 mM and in water to 10 mM.
• 使用に関する注意

  Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

  Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

• 由来

  ripe seeds of African plants Strophanthus gratus and the bark of Acokanthera ouabaio

• 研究分野
  • Neuroscience
  • Neurotransmitter
  • Transporters
  • Other Transporters

  • Biochemicals
  • Product Range
  • Just Add Water

  • Biochemicals
  • Chemical Type
  • Biochemicals

  • Biochemicals
  • Pharmacology
  • Receptors & Transporters
  • Transporters
  • Ion pumps / transporter
  • Na⁺/K⁺ cotransporter
  • Inhibitor