Anti-Osteocalcin 抗体 (ab93876)
Key features and details
- Rabbit polyclonal to Osteocalcin
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
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製品名
Anti-Osteocalcin antibody
Osteocalcin 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Osteocalcin -
由来種
Rabbit -
アプリケーション
適用あり: WB, IHC-Pmore details -
種交差性
交差種: Mouse, Human -
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
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ポジティブ・コントロール
- IHC-P: Liver carcinoma tissue WB: Lung tissue lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
バッファー
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: PBS, 1% BSA -
Concentration information loading...
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精製度
Protein A purified -
特記事項(精製)
Affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab93876の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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WB |
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa.
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IHC-P | (3) |
Use at an assay dependent concentration.
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特記事項 |
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WB
Use at an assay dependent concentration. Predicted molecular weight: 11 kDa. |
IHC-P
Use at an assay dependent concentration. |
ターゲット情報
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機能
Constitutes 1-2% of the total bone protein. It binds strongly to apatite and calcium. -
配列類似性
Belongs to the osteocalcin/matrix Gla protein family.
Contains 1 Gla (gamma-carboxy-glutamate) domain. -
翻訳後修飾
Gamma-carboxyglutamate residues are formed by vitamin K dependent carboxylation. These residues are essential for the binding of calcium. -
細胞内局在
Secreted. - Information by UniProt
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参照データベース
- Entrez Gene: 632 Human
- Entrez Gene: 12096 Mouse
- Omim: 112260 Human
- SwissProt: P02818 Human
- SwissProt: P86546 Mouse
- Unigene: 654541 Human
- Unigene: 389459 Mouse
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別名
- BGLAP antibody
- BGP antibody
- Bone gamma carboxyglutamate (gla) protein antibody
see all
画像
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Anti-Osteocalcin antibody (ab93876) at 1/100 dilution + Mouse lung tissue lysate
Predicted band size: 11 kDaWestern blot analysis of mouse lung tissue lysate with anti-osteocalcin antibody.
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Immunohistochemical staining of formalin-fixed paraffin-embedded liver carcinoma staining with anti-osteocalcin antibody at a dilution of 1/100.
プロトコール
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (288)
ab93876 は 288 報の論文で使用されています。
- Wu C et al. Mapk7 deletion in chondrocytes causes vertebral defects by reducing MEF2C/PTEN/AKT signaling. Genes Dis 11:964-977 (2024). WB ; Mouse . PubMed: 37692479
- Sun B et al. Irisin reduces bone fracture by facilitating osteogenesis and antagonizing TGF-β/Smad signaling in a growing mouse model of osteogenesis imperfecta. J Orthop Translat 38:175-189 (2023). PubMed: 36439629
- Luo J et al. Cerium Oxide Nanoparticles Promote Osteoplastic Precursor Differentiation by Activating the Wnt Pathway. Biol Trace Elem Res 201:865-873 (2023). PubMed: 35230639
- Luzuriaga J et al. Osteogenic differentiation of human dental pulp stem cells in decellularised adipose tissue solid foams. Eur Cell Mater 43:112-129 (2022). PubMed: 35312032
- Song YQ et al. Identification of PDXDC1 as a novel pleiotropic susceptibility locus shared between lumbar spine bone mineral density and birth weight. J Mol Med (Berl) 100:723-734 (2022). PubMed: 35314877