製品の概要

  • 製品名Anti-OSBP1 antibody
    OSBP1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to OSBP1
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rabbit
  • 免疫原

    Synthetic peptide: CKEKQDWSSCPDIF, corresponding to C terminal amino acids 407-420 of Human OSBP1.

  • 特記事項GenBank Accession Number – NP_002547

製品の特性

関連製品

アプリケーション

Our Abpromise guarantee covers the use of ab5915 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
  • 追加情報Peptide ELISA: antibody detection limit dilution >1/16000
    WB: Use at a concentration of 1 - 3 µg/ml. Predicted molecular weight: 89.4 kDa.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能Binds cholesterol and a range of oxysterols. Cholesterol binding promotes the formation of a complex with PP2A and a tyrosine phosphatase which dephosphorylate ERK1/2, whereas 25-hydroxycholesterol causes its disassembly. Regulates cholesterol efflux by decreasing ABCA1 stability.
    • 組織特異性Widely expressed.
    • 配列類似性Belongs to the OSBP family.
      Contains 1 PH domain.
    • ドメインThe PH and Ala/Gly-rich domains control cholesterol binding without affecting 25-hydroxycholesterol binding.
      The second coiled-coil domain is required for interaction with the tyrosine phosphatase.
    • 細胞内局在Cytoplasm. Golgi apparatus membrane. When bound to oxysterols, translocates to the periphery of Golgi membranes.
    • Information by UniProt
    • 参照データベース
    • 別名
      • OSBP 1 antibody
      • OSBP antibody
      • OSBP1_HUMAN antibody
      • Oxysterol binding protein 1 antibody
      • Oxysterol-binding protein 1 antibody
      see all

    Anti-OSBP1 antibody 画像

    Anti-OSBP1 antibody (ab5915) 使用論文

    ab5915 has not yet been referenced specifically in any publications.

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    There are currently no Abreviews or Questions for ab5915.
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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"