製品の概要

  • 製品名Anti-ORP8 antibody
    ORP8 一次抗体 製品一覧
  • 製品の詳細
    Mouse polyclonal to ORP8
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human ORP8 protein (NP_001003712.1).

  • ポジティブ・コントロール
    • ORP8 transfected 293T cell lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab70056 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/500 - 1/1000. Detects a band of approximately 120 kDa (predicted molecular weight: 97 kDa).

ターゲット情報

  • 関連性ORP8 is a member of the oxysterol-binding protein related protein family. In humans, the gene family consists of 12 members, and extensive splice variation increases the number of encoded protein products substantially. The ORPs have been implicated as sterol sensors that regulate a number of cellular functions including sterol and neutral lipid metabolism, intracellular lipid transport, membrane trafficking and cell signaling. ORP8 has been recently shown to act as a sterol sensor that affects the reverse cholesterol transport process via modulation of ABCA1 expression and macrophage cholesterol efflux.
  • 細胞内局在Endoplasmic reticulum
  • 参照データベース
  • 別名
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Anti-ORP8 antibody 画像

  • All lanes : Anti-ORP8 antibody (ab70056) at 1/500 dilution

    Lane 1 : ORP8 transfected 293T lysate
    Lane 2 : Non-transfected 293T lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

    Predicted band size : 97 kDa
    Observed band size : 120 kDa (why is the actual band size different from the predicted?)

Anti-ORP8 antibody (ab70056) 使用論文

ab70056 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"