製品の概要

  • 製品名Anti-ORMDL3 antibody
    ORMDL3 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to ORMDL3
  • 特異性ab107639 may cross-react with ORMDL1 and ORMDL2.
  • アプリケーション適用あり: WBmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide corresponding to Human ORMDL3 aa 53-81 (internal sequence) conjugated to Keyhole Limpet Haemocyanin (KLH).
    Database link: Q8N138

  • ポジティブ・コントロール
    • WB: Mouse testis tissue lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab107639 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/1000. Predicted molecular weight: 17 kDa.

ターゲット情報

  • 機能Negative regulator of sphingolipid synthesis. May indirectly regulate endoplasmic reticulum-mediated Ca(+2) signaling.
  • 組織特異性Widely expressed. Expressed in adult and fetal heart, brain, lung, liver, skeletal muscle and kidney. Expressed in adult pancreas and placenta and in fetal spleen abd thymus.
  • 関連疾患Genetic variations in ORMDL3 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
  • 配列類似性Belongs to the ORM family.
  • 細胞内局在Endoplasmic reticulum membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • ORM1 (S. cerevisiae)-like 3 antibody
    • ORM1-like 3 (S. cerevisiae) antibody
    • ORM1-like 3 antibody
    • ORM1-like protein 3 antibody
    • ORMDL sphingolipid biosynthesis regulator 3 antibody
    • Ormdl3 antibody
    • ORML3_HUMAN antibody
    • OTTHUMP00000164334 antibody
    see all

Anti-ORMDL3 antibody 画像

  • All lanes : Anti-ORMDL3 antibody (ab107639) at 1/1000 dilution

    Lane 1 : Jurkat whole cell lysate
    Lane 2 : Mouse testis lysate

    Lysates/proteins at 20 µg per lane.

    Secondary
    Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution

    Predicted band size : 17 kDa

    Blocking buffer 5% NFDM/TBST
    Diluting buffer  5% NFDM/TBST

Anti-ORMDL3 antibody (ab107639) 使用論文

This product has been referenced in:
  • Zhuang LL  et al. Promoter characterization and role of cAMP/PKA/CREB in the basal transcription of the mouse ORMDL3 gene. PLoS One 8:e60630 (2013). WB ; Mouse . Read more (PubMed: 23577138) »

See 1 Publication for this product

Product Wall

Thank you for your reply and apologies for the mix up in my original response.

For both ab107639 and ab128660, we do guarantee that they will recognize the endogenous forms of the protein. For both antibodies, there are western blot images on ...

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Thank you for contacting Abcam.

If you wish a positive control to run in western blotting, then I would recommend the following GFP protein:

http://www.abcam.com/GFP-protein-ab84191.html.



If there is anything else I...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"