製品の概要

  • 製品名
    Anti-Orexin Receptor 2 antibody
    Orexin Receptor 2 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Orexin Receptor 2
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
    交差が予測される動物種: Rat, Dog, Pig
  • 免疫原

    Synthetic peptide corresponding to Human Orexin Receptor 2 aa 2-14 (N terminal).
    Sequence:

    SGTKLEDSPPCRN

  • ポジティブ・コントロール
    • WB: Human brain (Hippocampus) lysate.

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab65093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 - 3 µg/ml. Detects a band of approximately 51 kDa (predicted molecular weight: 51 kDa).

ターゲット情報

  • 機能
    Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
  • 配列類似性
    Belongs to the G-protein coupled receptor 1 family.
  • ドメイン
    The N-terminal region is required for orexin signaling.
  • 細胞内局在
    Cell membrane.
  • Information by UniProt
  • 参照データベース
  • 別名
    • Hcr tr2 antibody
    • Hcrt receptor 2 antibody
    • Hcrtr2 antibody
    • Hypocretin (orexin) receptor 2 antibody
    • Hypocretin receptor 2 antibody
    • Hypocretin receptor type 2 antibody
    • Orexin 2 receptor antibody
    • Orexin A/Orexin B receptor antibody
    • Orexin receptor 2 antibody
    • Orexin receptor type 2 antibody
    • Orexin type 2 receptor antibody
    • Ox-2-R antibody
    • Ox2-R antibody
    • Ox2r antibody
    • OX2R_HUMAN antibody
    • Type 2 hypocretin receptor antibody
    • Type 2 orexin receptor antibody
    see all

画像

  • Anti-Orexin Receptor 2 antibody (ab65093) at 1 µg/ml + Human brain (Hippocampus) lysate (in RIPA buffer). at 35 µg
    Developed using the ECL technique

    Predicted band size : 51 kDa
    Observed band size : 51 kDa

    Primary incubation was 1 hour.

プロトコール

参考文献

This product has been referenced in:
  • Ahmed SS  et al. Antibodies to influenza nucleoprotein cross-react with human hypocretin receptor 2. Sci Transl Med 7:294ra105 (2015). Read more (PubMed: 26136476) »

See 1 Publication for this product

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