Anti-Orexin Receptor 2 抗体 (ab115024)

製品の概要

• 製品名
  Anti-Orexin Receptor 2 antibody
  Orexin Receptor 2 一次抗体 製品一覧
• 製品の詳細
  Goat polyclonal to Orexin Receptor 2
• アプリケーション
  適用あり: WBmore details
• 種交差性
  交差種: Mouse
  交差が予測される動物種: Rat, Horse, Cow, Dog, Human, Pig
• 免疫原

  Synthetic peptide:

  C-KSLTTQISNFDNISK

  , corresponding to internal sequence amino acids (near the C terminus) 405-419 of Human Orexin Receptor 2 (NP_001517.2).

  Run BLAST with Run BLAST with
• ポジティブ･コントロール
  • Mouse fetal brain lysate.

製品の特性

• 製品の状態
  Liquid
• 保存方法
  Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
• バッファー
  pH: 7.30
  Preservative: 0.02% Sodium azide
  Constituents: 0.5% BSA, 99% Tris buffered saline
• Concentration information loading...
• 精製度
  Immunogen affinity purified
• 特記事項（精製）
  ab115024 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
• ポリ/モノ
  ポリクローナル
• アイソタイプ
  IgG
• 研究分野
  • Neuroscience
  • Neurotransmission
  • Receptors / Channels
  • GPCR
  • More GPCR

  • Signal Transduction
  • Signaling Pathway
  • G Protein Signaling
  • GPCR

  • Metabolism
  • Types of disease
  • Obesity

関連製品

• Compatible Secondaries
  • Donkey Anti-Goat IgG H&L (Alexa Fluor® 488) (ab150129)
  • Donkey Anti-Goat IgG H&L (HRP) (ab205723)

アプリケーション

ターゲット情報

• 機能
  Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
• 配列類似性
  Belongs to the G-protein coupled receptor 1 family.
• ドメイン
  The N-terminal region is required for orexin signaling.
• 細胞内局在
  Cell membrane.

• Target information above from: UniProt accession O43614 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 参照データベース
  • Entrez Gene: 529603 Cow
  • Entrez Gene: 399545 Dog
  • Entrez Gene: 100056772 Horse
  • Entrez Gene: 3062 Human
  • Entrez Gene: 387285 Mouse
  • Entrez Gene: 397428 Pig
  • Entrez Gene: 25605 Rat
  • Omim: 602393 Human

  • SwissProt: Q9TUP7 Dog
  • SwissProt: O43614 Human
  • SwissProt: P58308 Mouse
  • SwissProt: O62809 Pig
  • SwissProt: P56719 Rat
  • Unigene: 151624 Human
  • Unigene: 699147 Human
  • Unigene: 335300 Mouse
  • Unigene: 9893 Rat

  see all
• 別名
  • Hcr tr2 antibody
  • Hcrt receptor 2 antibody
  • Hcrtr2 antibody

  • Hypocretin (orexin) receptor 2 antibody
  • Hypocretin receptor 2 antibody
  • Hypocretin receptor type 2 antibody
  • Orexin 2 receptor antibody
  • Orexin A/Orexin B receptor antibody
  • Orexin receptor 2 antibody
  • Orexin receptor type 2 antibody
  • Orexin type 2 receptor antibody
  • Ox-2-R antibody
  • Ox2-R antibody
  • Ox2r antibody
  • OX2R_HUMAN antibody
  • Type 2 hypocretin receptor antibody
  • Type 2 orexin receptor antibody

  see all

プロトコール

• Western blot protocols