製品の概要
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製品名Anti-Orexin Receptor 2 antibody
Orexin Receptor 2 一次抗体 製品一覧 -
製品の詳細Goat polyclonal to Orexin Receptor 2
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由来種Goat
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アプリケーション適用あり: WBmore details
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種交差性交差種: Mouse
交差が予測される動物種: Rat, Horse, Cow, Dog, Human, Pig
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免疫原
Synthetic peptide:
C-KSLTTQISNFDNISK
, corresponding to internal sequence amino acids (near the C terminus) 405-419 of Human Orexin Receptor 2 (NP_001517.2). -
ポジティブ･コントロール
- Mouse fetal brain lysate.
製品の特性
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製品の状態Liquid
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保存方法Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
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バッファーpH: 7.30
Preservative: 0.02% Sodium azide
Constituents: 0.5% BSA, 99% Tris buffered saline -
Concentration information loading... -
精製度Immunogen affinity purified
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特記事項（精製）ab115024 was purified from Goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
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ポリ/モノポリクローナル
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アイソタイプIgG
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研究分野
関連製品
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Compatible Secondaries
アプリケーション
Our Abpromise guarantee covers the use of ab115024 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| アプリケーション | Abreviews | 特記事項 |
|---|---|---|
| WB | Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 50 kDa (predicted molecular weight: 53 kDa). |
ターゲット情報
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機能Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides (PubMed:9491897, PubMed:26950369). Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding (PubMed:9491897, PubMed:26950369).
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配列類似性Belongs to the G-protein coupled receptor 1 family.
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ドメインThe N-terminal region is required for orexin signaling.
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細胞内局在Cell membrane.
- Information by UniProt
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参照データベース
- Entrez Gene: 529603 Cow
- Entrez Gene: 399545 Dog
- Entrez Gene: 100056772 Horse
- Entrez Gene: 3062 Human
- Entrez Gene: 387285 Mouse
- Entrez Gene: 397428 Pig
- Entrez Gene: 25605 Rat
- Omim: 602393 Human
see all -
別名
- Hcr tr2 antibody
- Hcrt receptor 2 antibody
- Hcrtr2 antibody
see all
画像
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Western blot - Anti-Orexin Receptor 2 antibody (ab115024)Anti-Orexin Receptor 2 antibody (ab115024) at 0.5 µg/ml + Mouse fetal brain lysate (in RIPA buffer) at 35 µg
Developed using the ECL technique.
Predicted band size: 53 kDa
Observed band size: 50 kDa (why is the actual band size different from the predicted?)
プロトコール
参考文献
ab115024 has not yet been referenced specifically in any publications.
レビューと Q&A
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"