Anti-Orexin A 抗体 [MM0500-8G22] (ab89886)
Key features and details
- Mouse monoclonal [MM0500-8G22] to Orexin A
- Suitable for: IHC-Fr
- Reacts with: Human
- Isotype: IgG1
製品の概要
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製品名
Anti-Orexin A antibody [MM0500-8G22]
Orexin A 一次抗体 製品一覧 -
製品の詳細
Mouse monoclonal [MM0500-8G22] to Orexin A -
由来種
Mouse -
アプリケーション
適用あり: IHC-Frmore details -
種交差性
交差種: Human -
免疫原
Recombinant fragment: PLPDCC RQK TCSCRLY EL LHGAGNHA A GILT, corresponding to amino acids 35-65 of Human Orexin A
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. -
バッファー
Constituent: PBS -
Concentration information loading...
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精製度
Protein G purified -
特記事項(精製)
The IgG fraction of culture supernatant was purified by Protein G affinity chromatography and 0.2 µm filtered. -
ポリ/モノ
モノクローナル -
クローン名
MM0500-8G22 -
アイソタイプ
IgG1 -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab89886の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
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IHC-Fr |
Use at an assay dependent concentration.
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特記事項 |
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IHC-Fr
Use at an assay dependent concentration. |
ターゲット情報
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関連性
Orexin A (hypocretin 1) a 33 amino acid peptide and orexin B (hypocretin 2), a 28 amino acid peptide, are both derived from a common 130 amino acid precursor, prepro orexin. Orexin A and Orexin B stimulate food consumption when administered intracerebroventricularly to rats. Orexin gene expression in the brain is highly restricted to distinct populations of neurons located in specific hypothalamic regions, including the lateral hypothalamic area (LHA), a region implicated in feeding behaviour. Orexin A and orexin B bind to and activate two closely related G protein coupled receptors (GPCRs), termed Orexin 1 (OX1) and Orexin 2 (OX2) receptors. Dysfunction of the orexin peptide system has been linked to narcolepsy. -
細胞内局在
Rough endoplasmic reticulum. Cytoplasmic vesicle. Cell junction, synapse. Note: Associated with perikaryal rough endoplasmic reticulum as well as cytoplasmic large granular vesicles at synapses. -
参照データベース
- Entrez Gene: 3060 Human
- Omim: 602358 Human
- SwissProt: O43612 Human
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別名
- HCRT antibody
- HCRT1 antibody
- HCRT2 antibody
see all
データシートおよび資料
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Datasheet download
参考文献 (0)
ab89886 は論文での使用が確認できていません。