Recombinant full length ORC2 protein (Human), with a tag. MW of the tag alone is 26kDa.
Jurkat cell lysate and human spleen tissue sections.
Abcam is committed to meeting high standards of ethical manufacturing and has decided to discontinue this product by July 2018 as it has been generated by the ascites method. We are sorry for any inconvenience this may cause.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at an assay dependent concentration. PubMed: 21029866
1/500 - 1/1000. Detects a band of approximately 62 kDa (predicted molecular weight: 66 kDa).
Use a concentration of 5 µg/ml.
Use at an assay dependent concentration.
Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication.