Anti-Oligodendrocyte Specific Protein 抗体 - Oligodendrocyte Marker (ab53041)
Key features and details
- Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker
- Suitable for: ICC, WB
- Reacts with: Mouse, Rat
- Isotype: IgG
リコンビナント抗体で、ロット間での高い再現性を実現
- 異なるロット間での安定した再現性
- 容易なスケールアップ
- 評価試験による特異性の確認済み
- 倫理基準に準拠 - アニマル・フリーの生産
製品の概要
-
製品名
Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker
Oligodendrocyte Specific Protein 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to Oligodendrocyte Specific Protein - Oligodendrocyte Marker -
由来種
Rabbit -
特異性
Whilst ab53041 has been generated using synthetic peptide corresponding to human Oligodendrocyte protein (C-terminal), the antibody has only been validated for use in mouse.
Detects endogenous levels of total Oligodendrocyte Specific Protein.
-
アプリケーション
適用あり: ICC, WBmore details -
種交差性
交差種: Mouse, Rat
交差が予測される動物種: Human -
免疫原
Synthetic peptide corresponding to Human Oligodendrocyte Specific Protein (C terminal).
Database link: O75508 -
ポジティブ・コントロール
- WB: Mouse brain extract.
-
特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
-
製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg+2 and Ca+2 -
Concentration information loading...
-
精製度
Immunogen affinity purified -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
-
Compatible Secondaries
-
Isotype control
-
Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab53041の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
ICC | (1) |
1/200.
|
WB | (1) |
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa).
|
特記事項 |
---|
ICC
1/200. |
WB
1/500 - 1/1000. Detects a band of approximately 22 kDa (predicted molecular weight: 22 kDa). |
ターゲット情報
-
機能
Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. -
配列類似性
Belongs to the claudin family. -
細胞内局在
Cell junction > tight junction. Cell membrane. - Information by UniProt
-
参照データベース
- Entrez Gene: 5010 Human
- Entrez Gene: 18417 Mouse
- Entrez Gene: 84588 Rat
- Omim: 601326 Human
- SwissProt: O75508 Human
- SwissProt: Q60771 Mouse
- SwissProt: Q99P82 Rat
- Unigene: 31595 Human
see all -
別名
- Claudin 11 antibody
- Claudin-11 antibody
- CLD11_HUMAN antibody
see all
画像
-
All lanes : Anti-Oligodendrocyte Specific Protein antibody - Oligodendrocyte Marker (ab53041) at 1/500 dilution
Lane 1 : Mouse brain extract
Lane 2 : Mouse brain extract with peptide
Predicted band size: 22 kDa
Observed band size: 22 kDaSecondary antibody - anti-rabbit HRP (ab6721)
プロトコール
データシートおよび資料
-
SDS download
-
Datasheet download
参考文献 (70)
ab53041 は 70 報の論文で使用されています。
- Filiou MD et al. Multi-Omics Analysis Reveals Myelin, Presynaptic and Nicotinate Alterations in the Hippocampus of G72/G30 Transgenic Mice. J Pers Med 12:N/A (2022). PubMed: 35207732
- Gargareta VI et al. Conservation and divergence of myelin proteome and oligodendrocyte transcriptome profiles between humans and mice. Elife 11:N/A (2022). PubMed: 35543322
- Webb SM et al. The incubation of cocaine craving is dissociated from changes in glial cell markers within prefrontal cortex and nucleus accumbens of rats. Addict Neurosci 3:N/A (2022). PubMed: 36034166
- Hosoya M et al. Development of the stria vascularis in the common marmoset, a primate model. Sci Rep 12:19811 (2022). PubMed: 36396805
- Maier-Begandt D et al. A venous-specific purinergic signaling cascade initiated by Pannexin 1 regulates TNFα-induced increases in endothelial permeability. Sci Signal 14:N/A (2021). PubMed: 33653920