製品の概要

  • 製品名Anti-Ogg1 antibody
    Ogg1 一次抗体 製品一覧
  • 製品の詳細
    Goat polyclonal to Ogg1
  • 特異性This antibody is expected to recognise isoform 1a only.
  • アプリケーション適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Synthetic peptide:

    DLRQSRHAQEPPAK

    by a Cysteine residue linker, corresponding to C terminal amino acids 322-335 of Human Ogg1

  • ポジティブ・コントロール
    • Human Brain (Cerebellum) lysate

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • バッファーPreservative: 0.02% Sodium Azide
    Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
  • Concentration information loading...
  • 精製度Immunogen affinity purified
  • 特記事項(精製)ab63942 was purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
  • ポリ/モノポリクローナル
  • アイソタイプIgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab63942 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB
ELISA
  • 追加情報ELISA: Use at an assay dependent dilution. Antibody detection limit dilution for peptide ELISA: 1/32000
    WB: Use at a concentration of 0.2 - 0.6 µg/ml. Detects a band of approximately 39 kDa (predicted molecular weight: 39 kDa).

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • ターゲット情報

    • 機能DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion.
    • 組織特異性Ubiquitous.
    • 関連疾患Defects in OGG1 may be a cause of renal cell carcinoma (RCC) [MIM:144700]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma.
    • 配列類似性Belongs to the type-1 OGG1 family.
    • 細胞内局在Mitochondrion; Nucleus and Nucleus > nucleoplasm. Nucleus speckle. Nucleus matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells.
    • Information by UniProt
    • 参照データベース
    • 別名
      • 8 hydroxyguanine DNA glycosylase antibody
      • 8 oxoguanine DNA glycosylase 1 antibody
      • 8 oxoguanine DNA glycosylase antibody
      • AP lyase antibody
      • DNA (apurinic or apyrimidinic site) lyase antibody
      • DNA apurinic or apyrimidinic site lyase antibody
      • DNA lyase antibody
      • DNA-(apurinic or apyrimidinic site) lyase antibody
      • HMMH antibody
      • HOGG 1 antibody
      • HOGG1 antibody
      • MMH antibody
      • MUTM antibody
      • N glycosylase antibody
      • Ogg 1 antibody
      • Ogg1 antibody
      • OGG1_HUMAN antibody
      • OGH 1 antibody
      • OGH1 antibody
      see all

    Anti-Ogg1 antibody 画像

    • Anti-Ogg1 antibody (ab63942) at 0.2 µg/ml + Human Brain (Cerebellum) lysate at 35 µg

      Predicted band size : 39 kDa
      Observed band size : 39 kDa

    Anti-Ogg1 antibody (ab63942) 使用論文

    ab63942 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab63942.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"