Anti-Ogg1 抗体 (ab62826)
Key features and details
- Goat polyclonal to Ogg1
- Suitable for: WB
- Reacts with: Rat
- Isotype: IgG
製品の概要
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製品名
Anti-Ogg1 antibody
Ogg1 一次抗体 製品一覧 -
製品の詳細
Goat polyclonal to Ogg1 -
由来種
Goat -
アプリケーション
適用あり: WBmore details -
種交差性
交差種: Rat
交差が予測される動物種: Mouse, Cow, Human -
免疫原
Synthetic peptide:
C-HPKTSQAKGPSPLANK
, corresponding to internal sequence amino acids 282-297 of Rat Ogg1 -
ポジティブ・コントロール
- Rat Spleen lysate
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 7.30
Preservative: 0.02% Sodium azide
Constituents: Tris buffered saline, 0.5% BSA -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab62826の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
WB | (3) |
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 39 kDa).
1 hour primary incubation is recommended for this product. |
特記事項 |
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WB
Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 37 kDa (predicted molecular weight: 39 kDa). 1 hour primary incubation is recommended for this product. |
ターゲット情報
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機能
DNA repair enzyme that incises DNA at 8-oxoG residues. Excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine (FAPY) from damaged DNA. Has a beta-lyase activity that nicks DNA 3' to the lesion. -
組織特異性
Ubiquitous. -
関連疾患
Defects in OGG1 may be a cause of renal cell carcinoma (RCC) [MIM:144700]. It is a heterogeneous group of sporadic or hereditary carcinoma derived from cells of the proximal renal tubular epithelium. It is subclassified into clear cell renal carcinoma (non-papillary carcinoma), papillary renal cell carcinoma, chromophobe renal cell carcinoma, collecting duct carcinoma with medullary carcinoma of the kidney, and unclassified renal cell carcinoma. -
配列類似性
Belongs to the type-1 OGG1 family. -
細胞内局在
Mitochondrion; Nucleus and Nucleus > nucleoplasm. Nucleus speckle. Nucleus matrix. Together with APEX1 is recruited to nuclear speckles in UVA-irradiated cells. - Information by UniProt
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参照データベース
- Entrez Gene: 4968 Human
- Entrez Gene: 18294 Mouse
- Entrez Gene: 81528 Rat
- Omim: 601982 Human
- SwissProt: O15527 Human
- SwissProt: O08760 Mouse
- SwissProt: O70249 Rat
- Unigene: 380271 Human
see all -
別名
- 8 hydroxyguanine DNA glycosylase antibody
- 8 oxoguanine DNA glycosylase 1 antibody
- 8 oxoguanine DNA glycosylase antibody
see all
画像
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Anti-Ogg1 antibody (ab62826) at 0.1 µg/ml + Rat Spleen lysate at 35 µg
Predicted band size: 39 kDa
Observed band size: 37 kDa why is the actual band size different from the predicted?
Detected by chemiluminescence
データシートおよび資料
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Datasheet download
参考文献 (0)
ab62826 は論文での使用が確認できていません。