製品の概要

  • 製品名
    Anti-OBFC1 antibody
  • 製品の詳細
    Mouse polyclonal to OBFC1
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Full length human OBFC1 protein (NP_079204.1).

  • ポジティブ・コントロール
    • Human spleen tissue lysate, HeLa cell lysate and OBFC1 transfected 293T cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 精製度
    Protein A purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab89250 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 42 kDa.

ターゲット情報

  • 機能
    Component of the CST complex, a complex that binds to single-stranded DNA and is required to protect telomeres from DNA degradation. The CST complex binds single-stranded DNA with high affinity in a sequence-independent manner, while isolated subunits bind DNA with low affinity by themselves. In addition to telomere protection, the CST complex has probably a more general role in DNA metabolism at non-telomeric sites.
  • 配列類似性
    Belongs to the STN1 family.
    Contains 1 OB DNA-binding domain.
  • 細胞内局在
    Nucleus. Chromosome > telomere.
  • Information by UniProt
  • 参照データベース
  • 別名
    • AAF 44 antibody
    • AAF44 antibody
    • Alpha accessory factor 44 antibody
    • bA541N10.2 antibody
    • CST complex subunit STN1 antibody
    • FLJ22559 antibody
    • Obfc1 antibody
    • Oligonucleotide/oligosaccharide binding fold containing 1 antibody
    • Oligonucleotide/oligosaccharide-binding fold-containing protein 1 antibody
    • OTTHUMP00000020417 antibody
    • OTTHUMP00000020418 antibody
    • Replication protein A 32 kDa subunit antibody
    • RP11-541N10.2 antibody
    • RPA 32 antibody
    • STN1 antibody
    • STN1_HUMAN antibody
    • Suppressor of cdc thirteen antibody
    • Suppressor of cdc thirteen homolog antibody
    see all

画像

  • Anti-OBFC1 antibody (ab89250) at 1 µg/ml + human spleen tissue lysate at 50 µg

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
  • Anti-OBFC1 antibody (ab89250) at 1 µg/ml + HeLa cell lysate at 50 µg

    Predicted band size : 42 kDa
    Observed band size : 42 kDa
  • All lanes : Anti-OBFC1 antibody (ab89250) at 1 µg/ml

    Lane 1 : OBFC1 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.


    Predicted band size : 42 kDa
    Observed band size : 42 kDa

プロトコール

参考文献

This product has been referenced in:
  • Stewart JA  et al. Human CST promotes telomere duplex replication and general replication restart after fork stalling. EMBO J 31:3537-49 (2012). Read more (PubMed: 22863775) »

See 1 Publication for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab89250.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録