製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to OAS1
  • アプリケーション
    適用あり: IHC-P, WBmore details
  • 種交差性
    交差種: Mouse, Human
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Pig, Chimpanzee
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 288-337 (RRQLTKPRPV ILDPADPTGN LGGGDPKGWR QLAQEAEAWL NYPCFKNWDG) of human OAS1 (NP_001027581).

  • ポジティブ・コントロール
    • Transfected 293T cell lysate

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • バッファー
    Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab86343 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
IHC-P Use at an assay dependent concentration.
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 46 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.
  • 配列類似性
    Belongs to the 2-5A synthase family.
  • 細胞内局在
    Mitochondrion. Nucleus. Microsome. Endoplasmic reticulum. Associated with different subcellular fractions such as mitochondrial, nuclear, and rough/smooth microsomal fractions.
  • Information by UniProt
  • 参照データベース
  • 別名
    • (2 5')oligo(A) synthetase 1 antibody
    • (2-5'')oligo(A) synthase 1 antibody
    • 2 5 Oligoadenylate Synthetase 1 antibody
    • 2 5' oligo A synthase 1 antibody
    • 2 5' oligo A synthetase 1 antibody
    • 2 5A synthase 1 antibody
    • 2 5A synthetase 1 antibody
    • 2' 5' oligo A synthetase 1 antibody
    • 2' 5' oligoadenylate synthetase 1 40/46kDa antibody
    • 2' 5' oligoadenylate synthetase 1 antibody
    • 2' 5' oligoisoadenylate synthetase 1 antibody
    • 2''-5''-oligoadenylate synthase 1 antibody
    • 2'5' oligo A synthetase 1 antibody
    • 2'5' oligoadenylate synthetase 1 antibody
    • 2'5' oligoisoadenylate synthetase 1 antibody
    • 2-5A synthase 1 antibody
    • E18/E16 antibody
    • IFI 4 antibody
    • IFI4 antibody
    • OAS 1 antibody
    • OAS1 antibody
    • OAS1_HUMAN antibody
    • OIAS antibody
    • OIASI antibody
    • p46/p42 OAS antibody
    see all

画像

  • Anti-OAS1 antibody (ab86343) at 1 µg/ml (in 5% skim milk / PBS buffer) + transfected 293T cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 46 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human small intestine tissue labelling OAS1 with ab86343.

参考文献

This product has been referenced in:
  • Li H  et al. Identification of a Sjögren's syndrome susceptibility locus at OAS1 that influences isoform switching, protein expression, and responsiveness to type I interferons. PLoS Genet 13:e1006820 (2017). WB ; Human . Read more (PubMed: 28640813) »
  • Yu L  et al. Functional Roles of Pattern Recognition Receptors That Recognize Virus Nucleic Acids in Human Adipose-Derived Mesenchymal Stem Cells. Biomed Res Int 2016:9872138 (2016). Read more (PubMed: 28105439) »

See all 7 Publications for this product

レビューと Q&A

There are currently no Customer reviews or Questions for ab86343.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

登録