製品の概要

  • 製品名
  • 製品の詳細
    Rabbit polyclonal to NYREN18
  • 由来種
    Rabbit
  • アプリケーション
    適用あり: WB, ELISA, IHC-Pmore details
  • 種交差性
    交差種: Mouse, Human
  • 免疫原

    Synthetic peptide conjugated to KLH selected within aa 100~125 of human NYREN18.

  • ポジティブ・コントロール
    • Mouse liver lysate. Human hepatocarcinoma tissue.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
  • バッファー
    Preservative: 0.09% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度
    Protein G purified
  • 特記事項(精製)
    This antibody is purified through a protein G column, eluted out with both high and low pH buffers, neutralized immediately after elution then followed by dialysis against PBS.
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab38438 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/100 - 1/500. Detects a band of approximately 71 kDa (predicted molecular weight: 71 kDa).
ELISA 1/1000.
IHC-P 1/50 - 1/100.

ターゲット情報

  • 機能
    Specific down-regulator of the NEDD8 conjugation system. Recruits NEDD8, UBD, and their conjugates to the proteasome for degradation. Isoform 1 promotes the degradation of NEDD8 more efficiently than isoform 2.
  • 組織特異性
    Widely expressed with lowest expression in the pancreas for isoform 1 and in leukocytes, liver, prostate and skeletal muscle for isoform 2.
  • 配列類似性
    Contains 3 UBA domains.
  • 細胞内局在
    Nucleus. Predominantly nuclear.
  • Information by UniProt
  • 参照データベース
  • 別名
    • BS4 antibody
    • NEDD8 ultimate buster 1 antibody
    • Negative regulator of ubiquitin like proteins 1 antibody
    • Negative regulator of ubiquitin-like proteins 1 antibody
    • NUB1 antibody
    • NUB1_HUMAN antibody
    • NUB1L antibody
    • NY REN 18 antibody
    • NYREN18 antibody
    • Renal carcinoma antigen NY-REN-18 antibody
    see all

画像

  • Anti-NYREN18 antibody (ab38438) at 1/100 dilution + Mouse liver lysate

    Predicted band size: 71 kDa
    Observed band size: 71 kDa
    Additional bands at: 14 kDa, 23 kDa, 30 kDa, 45 kDa. We are unsure as to the identity of these extra bands.

  • Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with ab38438, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining

参考文献

ab38438 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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