製品の概要

  • 製品名
    Anti-NUDT15 antibody
  • 製品の詳細
    Rabbit polyclonal to NUDT15
  • アプリケーション
    適用あり: WBmore details
  • 種交差性
    交差種: Mouse
    交差が予測される動物種: Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog, Human, Saccharomyces cerevisiae
  • 免疫原

    Synthetic peptide corresponding to a region within internal sequence amino acids 33-82 (

    RKGSFGAGSFQLPGGHLEFGETWEECAQRETWEEAGLHLKNVCFASVVNS

    ) of Mouse NUDT15 (NP_766115).

  • ポジティブ・コントロール
    • Mouse small intestine lysate.

製品の特性

  • 製品の状態
    Liquid
  • 保存方法
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • バッファー
    Constituents: 97% PBS, 2% Sucrose
  • Concentration information loading...
  • 精製度
    Immunogen affinity purified
  • ポリ/モノ
    ポリクローナル
  • アイソタイプ
    IgG
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab122958 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 19 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

ターゲット情報

  • 機能
    Mediates the hydrolysis of some nucleoside diphosphate derivatives. Can degrade 8-oxo-dGTP in vitro, suggesting that it may remove an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine) from DNA and the nucleotide pool, thereby preventing misincorporation of 8-oxo-dGTP into DNA thus preventing A:T to C:G transversions. Its substrate specificity in vivo however remains unclear (By similarity). May have a role in DNA synthesis and cell cycle progression throught the interaction with PCNA.
  • 配列類似性
    Belongs to the Nudix hydrolase family.
    Contains 1 nudix hydrolase domain.
  • Information by UniProt
  • 参照データベース
  • 別名
    • 8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody
    • 8-oxo-dGTPase NUDT15 antibody
    • A730068G11Rik antibody
    • EC 3.1.6.- antibody
    • FLJ10956 antibody
    • MGC104352 antibody
    • MTH2 antibody
    • MutT homolog 2 antibody
    • Nucleoside diphosphate-linked moiety X motif 15 antibody
    • NUD15_HUMAN antibody
    • Nudix (nucleoside diphosphate linked moiety X)-type motif antibody
    • Nudix motif 15 antibody
    • NUDT15 antibody
    • OTTHUMP00000018389 antibody
    • Probable 7 antibody
    • Probable 7,8-dihydro-8-oxoguanine triphosphatase NUDT15 antibody
    • RP11-90M2.1 antibody
    see all

画像

  • Anti-NUDT15 antibody (ab122958) at 1 µg/ml + Mouse small intestine lysate at 10 µg

    Predicted band size : 19 kDa

プロトコール

参考文献

ab122958 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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