Anti-Nucleus and Mitotic Cell Antigen 抗体 [2Q2257] (ab64608)

製品の概要

  • 製品名Anti-Nucleus and Mitotic Cell Antigen antibody [2Q2257]
  • 製品の詳細
    Mouse monoclonal [2Q2257] to Nucleus and Mitotic Cell Antigen
  • 特異性ab64608 reacts with the cell nucleus and mitotic cell antigen (poles of the mitotic spindle and adjacent micotubules, centrosomes). It is possibly related to the NuMA protein. By Western blot this antibody recognizes a major band at 210kD, preferentially in mitotic cells (additional weaker bands at 240 and 180kD).
  • アプリケーション適用あり: WB, IHC-Frmore details
  • 種交差性
    交差種: Human
  • 免疫原

    Live Ls 174T cells (colonic carcinoma).

製品の特性

  • 製品の状態Liquid
  • 保存方法Shipped at 4°C. Store at +4°C short term (1-2 weeks). Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • バッファーPreservative: 0.1% Sodium Azide
    Constituents: PBS
  • Concentration information loading...
  • 精製度Purified IgM
  • ポリ/モノモノクローナル
  • クローン名2Q2257
  • アイソタイプIgM
  • 研究分野

アプリケーション

Our Abpromise guarantee covers the use of ab64608 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB Use at an assay dependent dilution. Detects a band of approximately 210 kDa.
IHC-Fr Use at an assay dependent dilution.

ターゲット情報

  • 関連性The life cycle of a eukaryotic cell consists of various phases, two of which can easily be identified. Firstly, during mitosis (M-phase), in which the cell divides into two identical daughter cells, chromosome condensation and spindle formation are microscopically visible. Secondly, in S-phase the DNA of a cell is replicated, a process that can be detected using biochemical techniques. In between the M and S phase two gap phases occur: the G1-phase, the gap between mitosis and the start of DNA replication, and G2-phase, the gap between completion of DNA replication and the onset of mitosis. From G1-phase a cell can leave the cell cycle and enter G0, a ‘quiescent’ phase. Regulation of the cell cycle predominantly occurs at three major control points, which govern the transition from G0 to G1, from G1 to S and from G2 to M-phase. The Nucleus and Mitotic Cell Antigen is an antigen detected at the poles of the mitotic spindle and adjacent micotubules and centrosomes.

Anti-Nucleus and Mitotic Cell Antigen antibody [2Q2257] (ab64608) 使用論文

ab64608 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"