製品の概要

  • 製品名
    Anti-Nucleostemin antibody
    Nucleostemin 一次抗体 製品一覧
  • 製品の詳細
    Rabbit polyclonal to Nucleostemin
  • アプリケーション
    適用あり: WB, ELISAmore details
  • 種交差性
    交差種: Human
  • 免疫原

    A KLH conjugated synthetic peptide selected from the Center region of human Nucleostemin.

  • ポジティブ・コントロール
    • HL60 cell line lysates

製品の特性

アプリケーション

Our Abpromise guarantee covers the use of ab64788 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

アプリケーション Abreviews 特記事項
WB 1/50 - 1/100. Detects a band of approximately 62 kDa (predicted molecular weight: 62 kDa).
ELISA 1/1000.

ターゲット情報

  • 機能
    May be required to maintain the proliferative capacity of stem cells and may play an important role in tumorigenesis.
  • 組織特異性
    Increased levels in lung tissue in cancer patients.
  • 配列類似性
    Belongs to the MMR1/HSR1 GTP-binding protein family.
    Contains 1 G (guanine nucleotide-binding) domain.
  • ドメイン
    The basic domain (B) allows nucleolar localization in the absence of GTP. The intermediate domain (I) inhibits nucleolar localization by the B domain and is required for exit from the nucleolus. Exit from the nucleolus to the nucleoplasm requires both the I and the acidic (A) domains, and may be triggered by GTP hydrolysis.
    In contrast to other GTP-binding proteins, this family is characterized by a circular permutation of the GTPase motifs described by a G4-G1-G3 pattern.
  • 細胞内局在
    Nucleus. Nucleus > nucleolus. Shuttles between the nucleus and nucleolus.
  • Information by UniProt
  • 参照データベース
  • 別名
    • C77032 antibody
    • E2 induced gene 3 protein antibody
    • E2-induced gene 3 protein antibody
    • E2IG3 antibody
    • Estradiol induced nucleotide binding protein antibody
    • GNL3 antibody
    • GNL3_HUMAN antibody
    • Guanine nucleotide binding protein like 3 (nucleolar) antibody
    • Guanine nucleotide binding protein like 3 antibody
    • Guanine nucleotide-binding protein-like 3 antibody
    • MGC800 antibody
    • NNP47 antibody
    • Novel nucleolar protein 47 antibody
    • NS antibody
    • Nucleolar GTP binding protein 3 antibody
    • Nucleolar GTP-binding protein 3 antibody
    • Nucleostemin antibody
    • Putative nucleotide binding protein estradiol induced antibody
    see all

画像

  • Anti-Nucleostemin antibody (ab64788) at 1/60 dilution + HL60 cell line lysates at 35 µg

    Predicted band size : 62 kDa
    Observed band size : 62 kDa

プロトコール

参考文献

ab64788 has not yet been referenced specifically in any publications.

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