Anti-NUCKS1 抗体 (ab84710)
Key features and details
- Rabbit polyclonal to NUCKS1
- Suitable for: IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
製品の概要
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製品名
Anti-NUCKS1 antibody
NUCKS1 一次抗体 製品一覧 -
製品の詳細
Rabbit polyclonal to NUCKS1 -
由来種
Rabbit -
アプリケーション
適用あり: IHC-Pmore details -
種交差性
交差種: Mouse, Human
交差が予測される動物種: Horse, Guinea pig, Chimpanzee, Rhesus monkey, Gorilla, Orangutan -
免疫原
Synthetic peptide, corresponding to a region within residues 1 and 50 of Human NUCKS1, NP_073568.2
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ポジティブ・コントロール
- Human breast carcinoma, prostate carcinoma, Mouse renal cell carcinoma
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特記事項
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
製品の特性
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製品の状態
Liquid -
保存方法
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
バッファー
pH: 6.8
Preservative: 0.09% Sodium azide
Constituents: 0.1% BSA, Tris buffered saline -
Concentration information loading...
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精製度
Immunogen affinity purified -
特記事項(精製)
Antibody concentration was determined by extinction coefficient: absorbance at 280 nm of 1.4 equals 1.0 mg of IgG. -
ポリ/モノ
ポリクローナル -
アイソタイプ
IgG -
研究分野
関連製品
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Compatible Secondaries
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Isotype control
アプリケーション
The Abpromise guarantee
Abpromise保証は、 次のテスト済みアプリケーションにおけるab84710の使用に適用されます
アプリケーションノートには、推奨の開始希釈率がありますが、適切な希釈率につきましてはご検討ください。
アプリケーション | Abreviews | 特記事項 |
---|---|---|
IHC-P |
1/100 - 1/500.
Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
特記事項 |
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IHC-P
1/100 - 1/500. Epitope exposure is recommended. Epitope exposure with citrate buffer will enhance staining. |
ターゲット情報
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翻訳後修飾
Phosphorylated by CDK1 and casein kinase. Phosphorylated upon DNA damage, probably by ATM or ATR. -
細胞内局在
Nucleus. - Information by UniProt
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参照データベース
- Entrez Gene: 64710 Human
- Entrez Gene: 98415 Mouse
- Omim: 611912 Human
- SwissProt: Q9H1E3 Human
- SwissProt: Q80XU3 Mouse
- Unigene: 213061 Human
- Unigene: 246869 Mouse
- Unigene: 392848 Mouse
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別名
- FLJ21480 antibody
- FLJ32016 antibody
- FLJ38536 antibody
see all
画像
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Detection of Human NUCKS1 by Immunofluorescence.
Sample: formalin fixed, paraffin embedded section of Human breast carcinoma.Antibody: ab84710 used at a dilution of 1/100.
Detection: Red-fluorescent goat anti-rabbit IgG highly cross-adsorbed Antibody Hilyte PlusTM 555 used at a dilution of 1/100. -
Detection of Human NUCKS1 by Immunohistochemistry.
Sample: FFPE section of Human prostate carcinoma.Antibody: ab84710 used at a dilution of 1/250.
Detection: DAB staining. -
Detection of Mouse NUCKS1 by Immunohistochemistry.
Sample: FFPE section of Mouse renal cell carcinoma.Antibody: ab84710 used at a dilution of 1/250.
Detection: DAB staining.
データシートおよび資料
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SDS download
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Datasheet download
参考文献 (3)
ab84710 は 3 報の論文で使用されています。
- Maranon DG et al. NUCKS1 promotes RAD54 activity in homologous recombination DNA repair. J Cell Biol 219:N/A (2020). PubMed: 32876692
- Gupta MK et al. Altered transcriptional regulatory proteins in glioblastoma and YBX1 as a potential regulator of tumor invasion. Sci Rep 9:10986 (2019). PubMed: 31358880
- Kikuchi A et al. Identification of NUCKS1 as a colorectal cancer prognostic marker through integrated expression and copy number analysis. Int J Cancer : (2012). IHC-P ; Human . PubMed: 23065711